Table of contents

  1. Front Matter
    Pages i-xii
  2. John M. Squire, Pradeep K. Luther, Edward P. Morris
    Pages 1-48
  3. Clarence E. Schutt, Uno Lindberg
    Pages 49-63
  4. Bernhard Brenner
    Pages 77-149
  5. Mary C. Reedy, Michael K. Reedy, Kenneth A. Taylor
    Pages 151-170
  6. B. A. Levine, A. J. G. Moir, I. P. Trayer, R. J. P. Williams
    Pages 171-209
  7. Thomas P. Burghardt, Katalin Ajtai
    Pages 211-239
  8. William F. Harrington, Michael E. Rodgers, Julien S. Davis
    Pages 241-263
  9. Leepo C. Yu, Richard J. Podolsky
    Pages 265-286
  10. Jeff Harford, John M. Squire
    Pages 287-320
  11. Back Matter
    Pages 321-327

About this book


Muscle cells provide a unique probe into the motile properties of all living systems. A full understanding of the molecular mechanisms within muscle cells is therefore important to many areas of biological research. It is now nearly 40 years since the postulation of the sliding filament model of muscle contraction yet only recently has sufficient evidence been produced to support a convincing model. This book marks a turning point in muscle research. It reviews the evidence that myosin cross-bridges do indeed swing on actin filaments during contraction, and starts to tackle the problems this raises: what are the geometrics of the attached states of cross-bridges on actin? How many states are there? What is the sequence of molecular events during muscle activation? And is the primary source of muscular force cross-bridge swinging or Helix-coil transition?


activation insects molecular mechanisms muscle protein

Editors and affiliations

  • John M. Squire
    • 1
  1. 1.Imperial College of Science, Technology and MedicineLondonUK

Bibliographic information

  • DOI
  • Copyright Information Macmillan Publishers Limited 1990
  • Publisher Name Palgrave, London
  • eBook Packages Engineering
  • Print ISBN 978-1-349-09816-3
  • Online ISBN 978-1-349-09814-9
  • Buy this book on publisher's site