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Dendritic Cells in Cancer

  • Russell D. Salter
  • Michael R. Shurin

Table of contents

  1. Front Matter
    Pages i-xvii
  2. ALTERATIONS OF THE DENDRITIC CELL SYSTEM IN CANCER

    1. Front Matter
      Pages 1-1
    2. Jessica Chu, Russell D. Salter
      Pages 1-10
    3. Michael R. Shurin, Michael T. Lotze
      Pages 11-30
    4. Mikhail M. Dikov, Irina S. Chekneva
      Pages 57-75
    5. Benjamin J. Daniel, Duane P. Jeansonne, Suzanne R. Thibodeaux, Tyler J. Curiel
      Pages 77-87
    6. Viktor Umansky, Dirk Schadendorf
      Pages 89-99
  3. Mechanisms of Dendritic Cell Dysfunction in Cancer

    1. Front Matter
      Pages 1-1
    2. Alberto Pinzon-Charry, J. Alejandro López
      Pages 103-117
    3. Roberta Valenti, Veronica Huber, Paola Filipazzi, Manuela Iero, Giorgio Parmiani, Licia Rivoltini
      Pages 119-128
    4. Zoltan Pos, Marianna Sabatino, Tara Spivey, Hui Liu, Andras Falus, Francesco M. Marincola
      Pages 157-170
    5. Annabelle Grolleau-Julius, Raymond L. Yung
      Pages 171-180
    6. Rachel Kohman, Alexander W. Kusnecov
      Pages 181-199
    7. Galina V. Shurin, Neil Amina, Michael R. Shurin
      Pages 201-216
  4. Role of Dendritic Cells in Tumor Escape

    1. Front Matter
      Pages 1-1
    2. Alexey Popov, Joachim L. Schultze
      Pages 219-229
    3. Anjli Kukreja
      Pages 243-256
    4. Michael W. Lipscomb, Walter J. Storkus, Amy K. Wesa
      Pages 257-268
  5. Dendritic Cells in Cancer: Clinical Aspects

    1. Front Matter
      Pages 1-1
    2. Zoya R. Yurkovetsky, Ghena N. Yurkovetsky
      Pages 271-289
    3. Alistair J. Cochran, Rong-Rong Huang, Eijun Itakura, Jonathan H. Lee, Barbara G. Molenkamp
      Pages 291-307
    4. Ezra D. Mirvish, Rebecca G. Pomerantz, Louis D. Falo, Larisa J. Geskin
      Pages 309-330
    5. Brian J. Morrison, Jason C. Steel, Melissa Gregory, John C. Morris, Anatoli M. Malyguine
      Pages 347-363
    6. Lourdes R. Ylagan
      Pages 365-374
    7. Madhav V. Dhodapkar
      Pages 375-383
  6. Back Matter
    Pages 385-396

About this book

Introduction

Significant features of cancer are suppression and redirection of the immune response, which allow for tumor development and growth in the previously immune competent host. Central to development of immune responses are dendritic cells, and unsurprisingly these cells are strongly impacted by tumors and factors derived from them, as well as by other conditions associated with tumor progression or cancer treatments. Further, as some of the frontline strategies for treatment of cancer involve immunotherapy with ex vivo cultured or in vivo modulated dendritic cells, it becomes imperative to understand how dendritic cells interact with and are affected by the tumor microenvironment. "Dendritic Cells in Cancer," edited by Michael R. Shurin and Russell D. Salter, presents thorough analyses of the complex biology of the tumor-dendritic cell relationship, and offers insights into how cancer treatments may benefit from furthering our understanding in this area.

Keywords

Activation Cancer Dendritic Cells Dendritic cell vaccines Endoplasmatisches Reticulum IDO Promoter Regulation Signaling pathways Tumor-infiltrating Vivo dendritic cell function immunity

Editors and affiliations

  • Russell D. Salter
  • Michael R. Shurin

There are no affiliations available

Bibliographic information