Table of contents

  1. Front Matter
    Pages i-x
  2. David S. Goodsell
    Pages 1-6
  3. David S. Goodsell
    Pages 8-26
  4. David S. Goodsell
    Pages 28-50
  5. David S. Goodsell
    Pages 52-68
  6. David S. Goodsell
    Pages 70-81
  7. David S. Goodsell
    Pages 82-107
  8. David S. Goodsell
    Pages 108-125
  9. David S. Goodsell
    Pages 126-138
  10. David S. Goodsell
    Pages 140-156
  11. Back Matter
    Pages 157-167

About this book


Imagine that we had some way to look directly at the molecules in a living organism. An x-ray microscope would do the trick, or since we’re dreaming, perhaps an Asimov-style nanosubmarine (unfortunately, neither is currently feasible). Think of the wonders we could witness firsthand: antibodies atta- ing a virus, electrical signals racing down nerve fibers, proteins building new strands of DNA. Many of the questions puzzling the current cadre of sci- tists would be answered at a glance. But the nanoscale world of molecules is separated from our everyday world of experience by a daunting million-fold difference in size, so the world of molecules is completely invisible. I created the illustrations in this book to help bridge this gulf and allow us to see the molecular structure of cells, if not directly, then in an artistic rendition. I have included two types of illustrations with this goal in mind: watercolor paintings which magnify a small portion of a living cell by one million times, showing the arrangement of molecules inside, and comput- generated pictures, which show the atomic details of individual molecules. In this second edition of The Machinery of Life, these illustrations are presented in full color, and they incorporate many of the exciting scientific advances of the 15 years since the first edition.


Escherichia coli Polysaccharid Virus Viruses biochemistry cell biology cellular processes current37 molecular biology molecular machines proteins

Authors and affiliations

  • David S. Goodsell
    • 1
  1. 1.Department of Molecular BiologyThe Scripps Research InstituteLa JollaUSA

Bibliographic information