Reelin Glycoprotein

Structure, Biology and Roles in Health and Disease

  • S. Hossein Fatemi

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. Cheng-Chiu Huang, Gabriella D’Arcangelo
    Pages 1-13
  3. Yves Jossin
    Pages 37-47
  4. Junichi Takagi
    Pages 57-67
  5. Eric C. Olson, Christopher A. Walsh
    Pages 89-105
  6. Rosalinda C. Roberts, Emma Perez-Costas
    Pages 107-125
  7. Toshio Ohshima
    Pages 127-139
  8. Robert F. Hevner
    Pages 141-158
  9. Eckart Förster, Shanting Zhao, Michael Frotscher
    Pages 159-169
  10. Shenfeng Qiu, Edwin John Weeber
    Pages 171-191
  11. Jonathan A. Cooper, Nathaniel S. Allen, Libing Feng
    Pages 193-216
  12. George D. Pappas, C. Sue Carter
    Pages 217-226
  13. Manuel Álvarez-Dolado
    Pages 227-235
  14. Thomas Ringstedt
    Pages 237-250
  15. Brigitte Samama, Nelly Boehm
    Pages 251-261
  16. Jean-Marc Mienville
    Pages 263-277
  17. Françoise Bleicher, Henry Magloire, Marie-Lise Couble, Jean-Christophe Maurin
    Pages 279-290

About this book

Introduction

Reelin glycoprotein is a major secretory protein with important roles in embryogenesis and during adult life. Reelin gene mutations or deficiency of the protein product cause abnormal cortical development and reelin signaling impairment in brain. Since the first discovery of the reelin mutant mouse in 1951 by Falconer, and later discovery of the gene for reelin in 1995, there has been an explosion of new knowledge about this important molecule. Reelin Glycoprotein: Structure, Biology and Roles in Health and Disease, written by an international panel of experts, summarizes the state of the knowledge on various aspects of reelin. Topics include the reelin gene and its receptors, downstream effector molecules in reelin signaling cascade, chemistry and structure of reelin, comparative anatomy of reelin, presence of reelin in various body tissues, reelin mutations, and abnormalities of reelin production in neuropsychiatric disorders and cancer. This book will serve as a foundation for analysis of this emerging novel protein for all neuroscientists and clinicians.

Keywords

Alzheimer Oxytocin alzheimer's disease anatomy autism brain cerebral cortex cognition cortex protein receptor schizophrenia stroke

Editors and affiliations

  • S. Hossein Fatemi
    • 1
  1. 1.Medical SchoolUniversity of MinnesotaMinneapolisUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-0-387-76761-1
  • Copyright Information Springer New York 2008
  • Publisher Name Springer, New York, NY
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-0-387-76760-4
  • Online ISBN 978-0-387-76761-1
  • About this book