Drug Addiction

From Basic Research to Therapy

  • Rao S. Rapaka
  • Wolfgang Sadée

Table of contents

  1. Front Matter
    Pages i-xxiii
  2. General Topics

    1. Per Svenningsson, Angus C. Nairn, Paul Greengard
      Pages 3-16
    2. Young-Won Chin, Marcy J. Balunas, Hee Byung Chai, A. Douglas Kinghorn
      Pages 17-39
    3. Michael J. Kuhar, Jason N. Jaworski, George W. Hubert, Kelly B. Philpot, Geraldina Dominguez
      Pages 101-112
    4. Madhavan P. N. Nair, Jessica L. Reynolds, Supriya D. Mahajan, Stanley A. Schwartz, Ravikumar Aalinkeel, B. Bindukumar et al.
      Pages 113-125
    5. Martin W. Adler, Ellen B. Geller, Xiaohong Chen, Thomas J. Rogers
      Pages 127-138
    6. Andrea Piserchio, Mark Spaller, Dale F. Mierke
      Pages 139-148
  3. Transporters & Stimulants & Hallucinogens

    1. Evan L. Riddle, Annette E. Fleckenstein, Glen R. Hanson
      Pages 169-177
    2. F. Ivy Carroll, James L. Howard, Leonard L. Howell, Barbara S. Fox, Michael J. Kuhar
      Pages 179-191
    3. Kellie J. White, Crystal C. Walline, Eric L. Barker
      Pages 193-215
    4. Thomas E. Prisinzano, Kevin Tidgewell, Wayne W. Harding
      Pages 231-245
    5. Richard B. Rothman, Bruce E. Blough, Michael H. Baumann
      Pages 311-326
    6. Anita H. Lewin
      Pages 327-339
  4. Drug Design: Nicotine, Opioids and Related Ligands

    1. Jeffrey R. Deschamps
      Pages 343-355
    2. Peter W. Schiller
      Pages 357-366
    3. Matthew D. Metcalf, Andrew Coop
      Pages 395-431
    4. Victor J. Hruby, Frank Porreca, Henry I. Yamamura, Gordon Tollin, Richard S. Agnes, Yeon Sun Lee et al.
      Pages 477-494
  5. Opioids: General

    1. Ken A. Witt, Thomas P. Davis
      Pages 511-533
    2. Achla Gupta, Fabien M. Décaillot, Lakshmi A. Devi
      Pages 547-558
    3. Irina D. Pogozheva, Magdalena J. Przydzial, Henry I. Mosberg
      Pages 559-584
    4. Brian E. Kane, Bengt Svensson, David M. Ferguson
      Pages 585-608
    5. Kirsten M. Raehal, Laura M. Bohn
      Pages 617-624
  6. Cannabinoid

  7. Back Matter
    Pages 765-782

About this book


Drug Addiction: From Basic Research to Therapy provides a comprehensive overview of physiological, biochemical, genetic and behavioral pathways underlying drug addiction. Focusing on fundamental neurophysiological processes that overlap between drug addiction and other CNS disorders, this volume covers the translation of basic research into novel therapies, not only of drug addiction but a spectrum of related CNS disorders, including pain. Chapters are written by leading scientists with widely ranging expertise in synthetic and computational chemistry, molecular biology, genetics, neurosciences, drug discovery and development, drug targeting, and quantitative therapeutics, providing an unprecedented overview of a complex field of high societal signficance.


Addiction Basic Cannabinoid Chemokine Drug Opioid Rapaka Research Sadee Therapy amphetamine cocaine dopamine drugs of abuse genetics

Editors and affiliations

  • Rao S. Rapaka
    • 1
  • Wolfgang Sadée
    • 2
  1. 1.National Institute on Drug AbuseBethesdaUSA
  2. 2.College of Medicine and Public HealthOhio State UniversityColumbusUSA

Bibliographic information