Transgenic Microalgae as Green Cell Factories

  • Rosa León
  • Aurora Galván
  • Emilio Fernández

Part of the Advances in Experimental Medicine and Biology book series (volume 616)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Rosa León, Emilio Fernández
    Pages 1-11
  3. Agustín Vioque
    Pages 12-22
  4. Markus Heitzer, Almut Eckert, Markus Fuhrmann, Christoph Griesbeck
    Pages 46-53
  5. Arthur R. Grossman
    Pages 54-76
  6. Aurora Galván, David González-Ballester, Emilio Fernández
    Pages 77-89
  7. Samuel P. Fletcher, Machiko Muto, Stephen P. Mayfield
    Pages 90-98
  8. Sathish Rajamani, Surasak Siripornadulsil, Vanessa Falcao, Moacir Torres, Pio Colepicolo, Richard Sayre
    Pages 99-109
  9. Anastasios Melis, Michael Seibert, Maria L. Ghirardi
    Pages 110-121
  10. Surasak Siripornadulsil, Konrad Dabrowski, Richard Sayre
    Pages 122-128
  11. Back Matter
    Pages 129-131

About this book


Microalgae have been largely cultured and commercialized as food and feed additives, and their potential as source of high-added value compounds is well known. But, in contrast to the large number of genetically modified bacteria, yeast and even higher plants, only a few species of microalgae have been genetically transformed with efficiency. Initial difficulties in the expression of foreign genes in microalgae have been progressively overcome, and powerful molecular tools for their genetic engineering are now on hand. A considerable collection of promoters and selectable marker genes and an increasing number of genomic or cDNA sequences have become available in recent years. More work is needed to transform new species of microalgae, specially those that have commercial value, so that it would be possible to increase the productivity of traditional compounds or synthesize novel ones. Silencing transgenes remains as an important limitation for stable expression of foreign genes. This problem is not unique to microalgae since it has also been observed in plants, animals and fungi. A better understanding of the mechanisms that control the regulation of gene expression in eukaryotes is therefore needed.

In this book a group of outstanding researchers working on different areas of microalgae biotechnology offer a global vision of the genetic manipulation of microalgae and their applications.


DNA Promoter algae cyanobacteria gene expression genes microalgae molecular biology

Editors and affiliations

  • Rosa León
    • 1
  • Aurora Galván
    • 2
  • Emilio Fernández
    • 2
  1. 1.Departamento de Química y Ciencia de Materiales, Facultad de Ciencias ExperimentalesUniversidad de HuelvaHuelvaSpain
  2. 2.Departamento de Bioquímica y Biología Molecular, Campus de RabanalesUniversidad de CórdobaCórdobaSpain

Bibliographic information