Table of contents

  1. Front Matter
    Pages i-xiv
  2. Genes, Neurons and Neurotransmission

    1. Front Matter
      Pages 1-1
    2. Bong-Kiun Kaang
      Pages 3-15
    3. Ling-Gang Wu, Jianhua Xu
      Pages 27-40
  3. Glutamate, Excitatory Transmission and Pain

    1. Front Matter
      Pages 41-41
    2. John F. MacDonald, Suhas Kotecha, Michael F. Jackson, Michael Beazely
      Pages 43-52
    3. Christophe Mulle
      Pages 53-62
    4. Rochelle Hines, Alaa El-Husseini
      Pages 63-84
    5. Megumu Yoshimura
      Pages 85-95
  4. Neuropeptides, ATP, Retrograde Messengers and Opioids

    1. Front Matter
      Pages 107-107
    2. Xu Zhang, Lan Bao
      Pages 109-115
    3. Terumasa Nakatsuka, Jianguo G. Gu
      Pages 117-130
    4. Zhizhong Z. Pan
      Pages 131-143
    5. Min Zhuo
      Pages 145-154
  5. Inhibitory Transmission and Plasticity

    1. Front Matter
      Pages 155-155
    2. Tian-Le Xu
      Pages 157-168
    3. Yves De Koninck
      Pages 169-184
  6. Postsynaptic Signaling and Gene Regulation

    1. Front Matter
      Pages 185-185
    2. Ronald A. Merrill, Stefan Strack
      Pages 187-205
    3. Haruhiko Bito, Sayaka Takemoto-Kimura, Hiroyuki Okuno
      Pages 207-217
    4. Kathleen A. Sluka, David A. Skyba, Marie K. Hoeger Bement, Katherine M. Audette, Rajan Radhakrishnan
      Pages 219-234
    5. Rohini Kuner
      Pages 235-244
  7. Peripheral Nociceptor, Amygdala and Fear

    1. Front Matter
      Pages 245-245
    2. Makoto Tominaga
      Pages 247-263
    3. Volker Neugebauer
      Pages 265-279
    4. Paul W. Frankland, Sheena A. Josselyn
      Pages 281-292
  8. Spinal Plasticity, Reorganization and Chronic Pain

  9. Cortical Plasticity, Reorganization and Amputation

    1. Front Matter
      Pages 335-335
    2. Min Zhuo
      Pages 337-349
    3. Huixin Qi, Jon H. Kaas
      Pages 351-369
  10. Endogenous Analgesia and Other Form of Analgesia

    1. Front Matter
      Pages 371-371
    2. Min Zhuo, Gerald F. Gebhart
      Pages 373-386
    3. Meredith Turnbach Robbins, Timothy J. Ness
      Pages 387-396
    4. Zhi-Qi Zhao
      Pages 397-411
    5. Zhizhong Z. Pan
      Pages 413-422
  11. Models for Studying Pain and Searching for Pain Killers

    1. Front Matter
      Pages 423-423
    2. Timothy J. Ness
      Pages 425-439
    3. Megumu Yoshimura
      Pages 459-467
    4. Annika B. Malmberg
      Pages 469-480
  12. Back Matter
    Pages 481-501

About this book


Molecular Pain is the first book to focus on molecular and synaptic mechanisms for pain transmission, modulation and plasticity. Unlike traditional textbooks about pain, this book covers recent progress in neuroscience and relates these developments to the basic mechanisms of chronic pain. The book also discusses current pain medicine and alternative pain treatments such as acupuncture.

Edited by a leading neuroscientist and pain researcher, Molecular Pain includes contributions by more than thirty international science experts from eight different countries. The book’s thirty-four chapters cover a wide spectrum of pain, analgesia, and neuroscience, and present chronic pain as a major health concern and a dynamic area of research.

Complete with 165 illustrations, Molecular Pain is a concise and comprehensive review of recent progress in the field of pain. This book is an invaluable reference work and textbook for advanced undergraduate students, graduate and medical students, and researchers in neuroscience, pain, animal behavior, anesthesiology and medicine.

Editors and affiliations

  • Min Zhuo
    • 1
  1. 1.Department of PhysiologyUniversity of TorontoTorontoCanada

Bibliographic information

  • DOI
  • Copyright Information Springer New York 2007
  • Publisher Name Springer, New York, NY
  • Print ISBN 978-0-387-75268-6
  • Online ISBN 978-0-387-75269-3
  • Buy this book on publisher's site