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Pediatric Inflammatory Bowel Disease

  • Petar Mamula
  • Jonathan E. Markowitz
  • Robert N. Baldassano

Table of contents

  1. Front Matter
    Pages I-XXXIII
  2. Etiology and Pathogenesis

    1. Front Matter
      Pages 1-1
    2. Nancy McGreal, Judy H. Cho
      Pages 3-14
    3. William A. Faubion, Claudio Fiocchi
      Pages 15-29
    4. Edwin F. de Zoeten, Ivan J. Fuss
      Pages 31-41
  3. Epidemiology and Clinical Features

    1. Front Matter
      Pages 43-43
    2. Shehzad Saeed, Subra Kugathasan
      Pages 45-60
    3. Michael D. Kappelman, Richard J. Grand
      Pages 83-90
    4. Shervin Rabizadeh, Maria Oliva-Hemker
      Pages 91-101
    5. Thomas D. Walters, Anne M. Griffiths
      Pages 103-117
    6. Barbara S. Kirschner, Barry H. Rich
      Pages 133-142
  4. Diagnosis

    1. Front Matter
      Pages 157-157
    2. Jennifer Strople, Benjamin D. Gold
      Pages 179-191
    3. Benedict C. Nwomeh, Wallace V. Crandall
      Pages 193-209
    4. Krishnappa Venkatesh, Mike Thomson
      Pages 211-240
    5. Marc Girardin, Ernest G. Seidman
      Pages 263-273
    6. Meena Thayu, Edisio Semeao, Mary B. Leonard
      Pages 275-294
  5. Medical Therapy

    1. Front Matter
      Pages 307-307
    2. Marla C. Dubinsky
      Pages 309-315
    3. M. Susan Moyer
      Pages 317-328
    4. Douglas Jacobstein, Howard Kader
      Pages 329-336
    5. Wael El Matary, Mary Zachos
      Pages 337-350
    6. David R. Mack
      Pages 351-361
    7. Johanna C. Escher
      Pages 363-369
    8. Carmen Cuffari
      Pages 371-378
    9. Joel R. Rosh
      Pages 379-386
    10. Sèverine Vermeire, Gert Van Assche, Paul Rutgeerts
      Pages 387-401
    11. Jeanne Tung, William J. Sandborn
      Pages 403-427
    12. Mark T. Osterman, Gary R. Lichtenstein
      Pages 429-446
    13. Harland Winter
      Pages 447-451
  6. Surgical Therapy

    1. Front Matter
      Pages 453-453
    2. Daniel von Allmen
      Pages 455-468
    3. Peter Mattei, John L. Rombeau
      Pages 469-483
    4. Christine Carter-Kent, Robert Wyllie
      Pages 485-494
    5. Susan N. Peck
      Pages 495-503
  7. Research

    1. Front Matter
      Pages 505-505
    2. Salvatore Cucchiara, Osvaldo Borrelli
      Pages 531-539
    3. Allan David Olson
      Pages 541-551
  8. Special Considerations

    1. Front Matter
      Pages 553-553
    2. Laura M Mackner, Wallace V Crandall
      Pages 555-563

About this book

Introduction

Pediatric Inflammatory Bowel Diseases (IBD) are the most common and most significant chronic disorders in Pediatric Gastroenterology. The onset of Crohn disease and ulcerative colitis in the first two decades of life presents a number of diagnostic and therapeutic challenges that are unique to pediatric patients. Although the studies available for pediatric diagnosis have improved dramatically in the past three decades, the improvement in technology alone cannot account for the increased frequency of IBD recognized in early childhood. While therapy for older patients has improved dramatically with the use of immunomodulators and the development of exciting biologic strategies, rarely if ever have comprehensive studies of the pharmacokinetics, safety and efficacy of any of the IBD medications been performed in pediatric patients. A number of excellent medications are not available in liquid preparations that can be swallowed by children, and others, such as timed-release formulations, are developed for delivery to an adult gastrointestinal tract. It is unfortunate that the care we provide to children is often an extrapolation of what is known about and available for adults with IBD. Pediatric patients with IBD face a number of unique challenges. The onset of disease before puberty can be devastating. Growth failure is a particularly difficult problem with potentially permanent consequences. Much of the pediatric specific research has focused on the role of nutritional therapy to treat growth failure and induce remission.

Keywords

Bone density Genetics Nutrition Therapeutics endoscopy

Editors and affiliations

  • Petar Mamula
    • 1
  • Jonathan E. Markowitz
    • 2
  • Robert N. Baldassano
    • 3
  1. 1.Attending Physician, Division of GI Hepatology and Nutrition, Director Endoscopy Suite, The Children’s Hospital of PhiladelphiaUniversity of Pennsylvania School of MedicinePhiladelphiaUSA
  2. 2.Attending Physician, Children’s Center for Digestive Health, Greenville Hospital System University Medical CenterUniversity of South Carolina School of MedicineGreenvilleUSA
  3. 3.Attending Physician and Director, Inflammatory Bowel Disease Center Division of GI, Hepatology and Nutrition. The Children’s Hospital of PhiladelphiaUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-0-387-73481-1
  • Copyright Information Springer Science+Business Media, LLC 2008
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine
  • Print ISBN 978-0-387-73480-4
  • Online ISBN 978-0-387-73481-1
  • Buy this book on publisher's site