Biopharmaceutics Applications in Drug Development

  • Rajesh Krishna
  • Lawrence Yu

Table of contents

  1. Front Matter
    Pages i-xxii
  2. Nancy P. Barbour, Robert A. Lipper
    Pages 1-25
  3. Sau Lawrence Lee, Andre S. Raw, Lawrence Yu
    Pages 47-74
  4. Xianhua Cao, Lawrence Yu, Duxin Sun
    Pages 75-100
  5. Hans E. Junginger
    Pages 139-174
  6. Rajinder K. Bhardwaj, Dea R. Herrera-Ruiz, Yan Xu, Stephen M. Carl, Thomas J. Cook, Nicholi Vorsa et al.
    Pages 175-261
  7. Sam H. Haidar, Hyojong (Hue) Kwon, Robert Lionberger, Lawrence Yu
    Pages 262-289
  8. William E. Bowen, Qingxi Wang, W. Peter Wuelfing, Denise L. Thomas, Eric D. Nelson, Yun Mao et al.
    Pages 290-316
  9. Banu S. Zolnik, Diane J. Burgess
    Pages 336-358
  10. Shoufeng Li, Alan E. Royce, Abu T. M. Serajuddin
    Pages 359-382
  11. Back Matter
    Pages 383-396

About this book


In the last two decades, the discipline of biopharmaceutics has undergone considerable advances, particularly with regard to bioavailability and bioequivalence as they relate to product quality and regulatory standards of approval. Textbooks in the field have not been able to keep up with the growth of current and emerging applications of regulatory aspects of biopharmaceutics.

Biopharmaceutics Applications in Drug Development fills this gap. This book introduces fundamental concepts, methods, and advances in the areas of dissolution, absorption, and permeability and their key applications in dosage form performance. Case studies are used to discuss the applications of biopharmaceutic strategies in the development of successful drugs, with a specific focus on the applications of biopharmaceutic strategies in the development of successful drugs. The book presents an integrated view in linking pharmaceutic to the biological consequences of drug products and leverages those for decision making in drug development.


absorption bioequivalence biomedicine biopharmaceuticals drug drug development kinetics pharmacokinetics protein

Editors and affiliations

  • Rajesh Krishna
    • 1
  • Lawrence Yu
    • 2
  1. 1.Merck & Co., Inc.RahwayUSA
  2. 2.Center for Drug Evaluation & ResearchRockvilleUSA

Bibliographic information