Book 2007

Alzheimer’s Disease

Advances in Genetics, Molecular and Cellular Biology

Editors:

ISBN: 978-0-387-35134-6 (Print) 978-0-387-35135-3 (Online)

Table of contents (15 chapters)

  1. Front Matter

    Pages i-ix

  2. No Access

    Chapter

    Pages 1-16

    The Genetics of Alzheimer’s Disease

  3. No Access

    Chapter

    Pages 17-34

    APP Biology, Processing and Function

  4. No Access

    Chapter

    Pages 35-58

    The Biology of the Presenilin Complexes

  5. No Access

    Chapter

    Pages 59-76

    β-secretase: Physiological Role and Target Validation

  6. No Access

    Chapter

    Pages 77-91

    Cognitive Impairment in Transgenic Aβ and Tau Models of Alzheimer’s Disease

  7. No Access

    Chapter

    Pages 93-111

    Cholesterol and β-Amyloid

  8. No Access

    Chapter

    Pages 113-131

    Aβ Structure and Aggregation

  9. No Access

    Chapter

    Pages 133-150

    Signaling Mechanisms that Mediate Aβ Induced Neuronal Dysfunction

  10. No Access

    Chapter

    Pages 151-156

    Beta Amyloid and Excitatory Synapses

  11. No Access

    Chapter

    Pages 157-178

    Aβ Degradation

  12. No Access

    Chapter

    Pages 179-198

    Role of A β Transport and Clearance in the Pathogenesis and Treatment of Alzheimer’s Disease

  13. No Access

    Chapter

    Pages 199-213

    Tau Gene Mutations in FTDP-17 Syndromes

  14. No Access

    Chapter

    Pages 215-236

    Animal Models of Tauopathy

  15. No Access

    Chapter

    Pages 237-256

    Tau and Axonal Transport

  16. No Access

    Chapter

    Pages 257-277

    Growth Factors in Alzheimer’s Disease

  17. Back Matter

    Pages 279-286