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Table of contents (39 chapters)
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Membrane Domain and Biological Function
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Front Matter
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Membrane Lipid Domain and Human Pathobiology
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Front Matter
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S1P Signaling and SIPR
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Front Matter
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About this book
Sphingolipids are fundamental to the structures of cell membranes, lipoproteins, and the stratum cornea of the skin. Many complex sphingolipids as well as simpler sphingoid bases and derivatives are highly bioactive as extra- and intracellular regulators of growth, differentiation, migration, survival, senescence, and numerous cellular responses to stress. This book provides many examples of exciting new developments in sphingolipid biology/sphingolipidology that are changing our understanding of how multicellular organisms grow, develop, function, age, and die. Key areas addressed include sphingolipid biosynthesis, transport and membrane organization/lipid rafts; genetic approaches to understanding the roles of membrane sphingolipid biosynthesis; sphingolipid metabolism, specific G protein-coupled receptors (GPCRs), and signal transduction; and sphingolipid-associated disease and drug development.
Editors and Affiliations
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Brain Science Institute, The Institute of Physical and Chemical Research (Riken), Saitama, Japan
Yoshio Hirabayashi
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Department of Biomembrane and Biofunctional Chemistry, Faculty of Advanced Life Science and Graduate School of Life Science, Hokkaido University, Sapporo, Japan
Yasuyuki Igarashi
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School of Biology and the Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, USA
Alfred H. Merrill
Bibliographic Information
Book Title: Sphingolipid Biology
Editors: Yoshio Hirabayashi, Yasuyuki Igarashi, Alfred H. Merrill
DOI: https://doi.org/10.1007/4-431-34200-1
Publisher: Springer Tokyo
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer-Verlag Tokyo 2006
Hardcover ISBN: 978-4-431-34198-7Published: 19 July 2006
Softcover ISBN: 978-4-431-54666-5Published: 02 December 2014
eBook ISBN: 978-4-431-34200-7Published: 31 December 2007
Edition Number: 1
Number of Pages: XXV, 531
Topics: Cell Biology, Biochemistry, general