Nimesulide — Actions and Uses

  • K.D. Rainsford

Table of contents

  1. Front Matter
    Pages i-xvi
  2. A. Bernareggi, K.D. Rainsford
    Pages 63-120
  3. A. Maroni, A. Gazzaniga
    Pages 121-132
  4. K.D. Rainsford, M. Bevilacqua, F. Dallegri, F. Gago, L. Ottonello, G. Sandrini et al.
    Pages 133-244
  5. M. Bianchi, G. E. Ehrlich, F. Facchinetti, E.C. Huskisson, P. Jenoure, A. La Marca et al.
    Pages 245-313
  6. I. Bjarnason, F. Bissoli, A. Conforti, L. Maiden, N. Moore, U. Moretti et al.
    Pages 315-415
  7. Back Matter
    Pages 417-433

About this book


Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) which acts as a cyclooxygenase- 2 inhibitor but also has other novel pharmacological features which account for its effect in the control of pain and inflammation. It has become a leading NSAID in over 50 countries worldwide.

This book provides a comprehensive and fully up-to-date critical review of the published literature on nimesulide, including comparisons with anti-inflammatory, analgesic and antipyretic agents. The emphasis is on the action of nimesulide in relation to its therapeutic and side effects in comparison with other established NSAIDs, including the new class of Coxibs.

The chapters are written by leading experts and cover development of nimesulide, including synthesis and production, introduction, and approved uses and applications, followed by pharmacokinetics and toxicological properties, adverse reactions and their mechanisms.


COX-2 Inhibitor drug inflammation kinetics pain pharmacokinetics

Editors and affiliations

  • K.D. Rainsford
    • 1
  1. 1.Biomedical Research CentreSheffield Hallam UniversitySheffieldUK

Bibliographic information