Cancer: Cell Structures, Carcinogens and Genomic Instability

Part of the Experientia Supplementum book series (EXS, volume 96)

Table of contents

  1. Front Matter
    Pages I-XI
  2. Leon P. Bignold, B. L. D. Coghlan, H. P. A. Jersmann
    Pages 1-24
  3. Bojan Drobic, Katherine L. Dunn, Paula S. Espino, James R. Davie
    Pages 25-47
  4. Sen Pathak, Asha S. Multani
    Pages 49-64
  5. Troy R. Durham, Elizabeth T. Snow
    Pages 97-130
  6. David I. Pattison, Michael J. Davies
    Pages 131-157
  7. Carmel Mothersill, C. B. Seymour
    Pages 159-177
  8. Karl Münger, Hiroyuki Hayakawa, Christine L. Nguyen, Nadja V. Melquiot, Anette Duensing, Stefan Duensing
    Pages 179-199
  9. Herman H. Cheung, Vinay Arora, Robert G. Korneluk
    Pages 201-221
  10. Marianne Sowa, Benjamin J. Arthurs, Brian J. Estes, William F. Morgan
    Pages 293-301
  11. Stavroula Raptis, Bharati Bapat
    Pages 303-320
  12. William B. Coleman, Gregory J. Tsongalis
    Pages 321-349
  13. Back Matter
    Pages 363-376

About this book


Tumors can be induced by a variety of physical and chemical carcinogens. The resulting tumor cells are usually abnormal in their morphology and behavior and transmit their abnormalities to their daughter tumor cells. Most theories of the pathogenesis of tumors suggest that carcinogens in some way cause alterations either of the genomes or of inheritable patterns of gene expression in normal cells, which then cause morphological and behavioral changes.

This volume presents a collection of articles aimed at the question by what genetic or epigenetic mechanisms carcinogens can cause morphological abnormalities of tumor cells. It includes reviews of cellular targets of known carcinogens, and presents varying viewpoints of how morphological abnormalities and the actions of carcinogens might be related.

The volume will be of interest to all those who are involved in cancer research or in the prevention, diagnosis or management of tumors in humans or animals.


angiogenesis animals apoptosis behavior cancer cancer research carcinogenesis cell gene expression genes genome pathogenesis prevention regulation tumor

Bibliographic information