Immunology and Immunopathogenesis of Malaria

  • Jean Langhorne

Part of the Current Topics in Microbiology and Immunology book series (CT MICROBIOLOGY, volume 297)

Table of contents

  1. Front Matter
    Pages I-XI
  2. A. H. Achtman, P. C. Bull, R. Stephens, J. Langhorne
    Pages 71-102
  3. C. Engwerda, E. Belnoue, A. C. Grüner, L. Rénia
    Pages 103-143
  4. J. G. Beeson, P. E. Duffy
    Pages 187-227
  5. Back Matter
    Pages 229-233

About this book

Introduction

Malaria is still a major global health problem, killing more than 1 million people every year. Almost all of these deaths are caused by Plasmodium falciparum, one of the four species of malaria parasites infecting humans. This high burden of mortality falls heavily on Sub-Saharan Africa, where over 90% of these deaths are thought to occur, and 5% of children die before the age of 5 years. The death toll from malaria is still growing, with malaria-specific mortality in young African children estimated to have doubled during the last twenty years. This increase has been associated with drug resistance of the parasite, spread of insecticide resistant mosquitoes, poverty, social and political upheaval, and lack of effective vaccines.

This collection of reviews addresses many of these important issues of malarial immunity and immunopathology. They are of interest not only to malariologists, but hopefully also to the broader immunological community. Strong interactions with, and feedback from immunologists working in other infectious diseases and in basic immunology will help us to move the field of malaria immunology and therapeutic intervention forward more quickly.

Keywords

Malaria anemia blood blood stage malaria infection diseases drug resistance infection infectious infectious disease infectious diseases parasite pathogenesis pathology resistance vaccine

Editors and affiliations

  • Jean Langhorne
    • 1
  1. 1.Division of ParasitologyNational Institute for Medical ResearchUK

Bibliographic information

  • DOI https://doi.org/10.1007/3-540-29967-X
  • Copyright Information Springer-Verlag Berlin Heidelberg 2005
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-3-540-25718-9
  • Online ISBN 978-3-540-29967-7
  • Series Print ISSN 0070-217X
  • About this book