About this book

Introduction

Time-correlated single photon counting (TCSPC) is a remarkable technique for recording low-level light signals with extremely high precision and picosecond-time resolution. TCSPC has developed from an intrinsically time-consuming and one-dimensional technique into a fast, multi-dimensional technique to record light signals. So this reference and text describes how advanced TCSPC techniques work and demonstrates their application to time-resolved laser scanning microscopy, single molecule spectroscopy, photon correlation experiments, and diffuse optical tomography of biological tissue. It gives practical hints about constructing suitable optical systems, choosing and using detectors, detector safety, preamplifiers, and using the control features and optimising the operating conditions of TCSPC devices. Advanced TCSPC Techniques is an indispensable tool for everyone in research and development who is confronted with the task of recording low-intensity light signals in the picosecond and nanosecond range.

Keywords

Diffuse optical tomography Fluorescence lifetime imaging Fluorescence lifetime spectroscopy Single molecule spectroscopy Time-correlated single photon counting fluorescence spectroscopy microscopy spectroscopy

Authors and affiliations

  • Wolfgang Becker
    • 1
  1. 1.Becker & Hickl GmbHBerlinGermany

Editors and affiliations

  • A. W. CastlemanJr.
    • 1
  • J.P. Toennies
    • 2
  • W. Zinth
    • 3
  1. 1.Department of ChemistryThe Pennsylvania State UniversityUniversity ParkUSA
  2. 2.Max-Planck-Institut für StrömungsforschungGöttingenGermany
  3. 3.Institut für Medizinische OptikUniversität MünchenMünchenGermany

Bibliographic information

  • DOI https://doi.org/10.1007/3-540-28882-1
  • Copyright Information Springer Berlin Heidelberg 2005
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-3-540-26047-9
  • Online ISBN 978-3-540-28882-4
  • Series Print ISSN 0172-6218
  • About this book