RHO Family GTPases

  • Ed. Manser

Part of the Proteins and Cell Regulation book series (PROR, volume 3)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Ed Manser
    Pages 1-18
  3. Stephanie Pellegrin, Harry Mellor
    Pages 19-29
  4. Darerca Owen, Helen R. Mott
    Pages 31-72
  5. Mingjian Lu, Kodi S. Ravichandran
    Pages 73-92
  6. Tom Jacobs, Christine Hall
    Pages 93-112
  7. Yoji Kawano, Takako Kaneko-Kawano, Takeshi Yoshimura, Saeko Kawabata, Kozo Kaibuchi
    Pages 113-136
  8. Cheng-Gee Koh, Louis Lim
    Pages 137-156
  9. Astrid Kraemer, Alpha S. Yap
    Pages 157-189
  10. Ivan De Curtis
    Pages 191-210
  11. Zhuo-Shen Zhao
    Pages 211-230
  12. Raffaella Sordella, Jeffrey Settleman
    Pages 231-263
  13. Christina H. Eng, Gregg G. Gundersen
    Pages 265-296
  14. Back Matter
    Pages 297-297

About this book


Humans contain more than 20 Rho type GTPases. This volume not only presents a detailed phylogenetic analysis of Rho proteins, but also discusses the possible origins of the human members. Such an analysis of human Rho GTPases has not previously been attempted.

The book includes an overview of how Rho GTPases become activated which is complemented by an extensive Chapter by Darerca Owen and Helen Mott who unravel the beautiful molecular details given to us by the many structural studies of Rho GTPases.

The key areas currently being investigated in relation to these ubiquitous proteins are described for both in vitro and in vivo systems. These are presented in a format that ensures the reader can approach the topic with minimal background knowledge, while ultimately bringing the subject to the level of an expert. Timely and highly authoritative, this volume illuminates newer findings, particularly as they relate to Rho proteins in vertebrate biology.


Regulation cell biology conservation genecell proteins signal transduction transcription

Editors and affiliations

  • Ed. Manser
    • 1
  1. 1.Institute of Molecular and Cell BiologySingapore

Bibliographic information