Power Laws, Scale-Free Networks and Genome Biology

  • Eugene V. Koonin
  • Yuri I. Wolf
  • Georgy P. Karev

Part of the Molecular Biology Intelligence Unit book series (MBIU)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Eivind Almaas, Albert-László Barabási
    Pages 1-11
  3. Kwang-Il Goh, Byungnam Kahng, Doochul Kim
    Pages 12-24
  4. Sergei Maslov, Kim Sneppen
    Pages 25-39
  5. Andreas Wagner
    Pages 40-52
  6. Georgy P. Karev, Yuri I. Wolf, Eugene V. Koonin
    Pages 65-85
  7. Nikolay V. Dokholyan, Eugene I. Shakhnovich
    Pages 86-105
  8. T. Gregory Dewey, David J. Galas
    Pages 106-122
  9. Sergey V. Buldyrev
    Pages 123-164
  10. S. Rackovsky
    Pages 194-205
  11. Pau Fernández, Ricard V. Solé
    Pages 206-225
  12. Erik van Nimwegen
    Pages 236-253
  13. Back Matter
    Pages 255-257

About this book


Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explaining the emergence of these features. The collection of chapters, contributed by both physicists and biologists, strives to address the problems in this field in a rigorous but not excessively mathematical manner and to represent different viewpoints, which is crucial in this emerging discipline. Each chapter includes, in addition to technical descriptions of properties of biological networks and evolutionary models, a more general and accessible introduction to the respective problems. Most chapters emphasize the potential of theoretical systems biology for discovery of new biological phenomena.


DNA evolution genes genetics genome mathematical modeling molecular biology protein regulation transcription

Authors and affiliations

  • Eugene V. Koonin
    • 1
  • Yuri I. Wolf
    • 1
  • Georgy P. Karev
    • 1
  1. 1.National Center for Biotechnology Information National Library of MedicineNational Institutes of HealthBethesdaUSA

Bibliographic information

  • DOI
  • Copyright Information and Springer Science+Business Media, Inc. 2006
  • Publisher Name Springer, Boston, MA
  • eBook Packages Physics and Astronomy
  • Print ISBN 978-0-387-25883-6
  • Online ISBN 978-0-387-33916-0
  • Buy this book on publisher's site