© 2005

Development of the Inner Ear

  • Matthew W. Kelley
  • Doris K. Wu
  • Arthur N. Popper
  • Richard R. Fay

Part of the Springer Handbook of Auditory Research book series (SHAR, volume 26)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Andrew K. Groves
    Pages 10-42
  3. Suzanne L. Mansour, Gary C. Schoenwolf
    Pages 43-84
  4. Sarah Pauley, Veronica Matei, Kirk W. Beisel, Bernd Fritzsch
    Pages 85-121
  5. Pamela J. Lanford, Matthew W. Kelley
    Pages 122-157
  6. Jane E. Bryant, Andrew Forge, Guy P. Richardson
    Pages 158-203
  7. Ronna Hertzano, Karen B. Avraham
    Pages 204-232
  8. Back Matter
    Pages 233-240

About this book


This book describes the embryonic development of the vertebrate inner ear in six chapters that span all aspects of inner ear development, from the induction of the otic placode through cellular morphogenesis, to the onset of auditory function. In each chapter, a particular aspect of development of the inner ear is examined in terms of both classic embryologic experiments and more recent advances using molecular biological techniques. The publication of this volume is particularly timely in light of recent significant advances in molecular biological and cellular imaging techniques. These changes have led to an explosion in the pace of developmental inner ear research that is clearly reflected in the chapters presented here. The book will serve as a useful resource for scientists who study inner ear biology, as well as developmental biologists who work in other systems, but have an interest in an overview of the developing ear. This book will also be a valuable resource for clinicians who wish to know more about the development of the ear and about the genetic and molecular factors that regulate its formation.

Matthew Kelley and Doris Wu are both Investigators at the National Institute on Deafness and other Communication Disorders at the National Institutes of Health, Bethesda, Maryland. Arthur N. Popper is Professor in the Department of Biology and Co-Director of the Center for Comparative and Evolutionary Biology of Hearing at the University of Maryland, College Park. Richard R. Fay is Director of the Parmly Hearing Institute and Professor of Psychology at Loyola University of Chicago.


Vertebrate biology cell development ear embryo genes hearing morphogenesis neurobiology

Editors and affiliations

  • Matthew W. Kelley
    • 1
  • Doris K. Wu
    • 2
  • Arthur N. Popper
    • 3
  • Richard R. Fay
    • 4
  1. 1.Section on Developmental Neuroscience, Porter Neuroscience Center, NIDCDNational Institutes of HealthBethesdaUSA
  2. 2.Section on Hair Cell Development and Regeneration, NIDCDNational Institutes of HealthRockvilleUSA
  3. 3.Department of BiologyUniversity of MarylandCollege ParkUSA
  4. 4.Parmly Hearing Institute and Department of PsychologyLoyola University of ChicagoChicagoUSA

Bibliographic information


From the reviews:

"Since I was committed to writing several comprehensive reviews about ear development, I had anticipated that the book would be of a great help in these endeavors and I was not disappointed. Typical of this series, the seven chapters are authoritative, thoughtful, and timely treatises … . there remains ample need for the deeper and more scholarly full-length treatises offered here. My looming sense of despair about ever staying abreast of the literature … has been mollified … through the valiant efforts of these authors." (Donna M-Fekete, The Quarterly Review of Biology, Vol. 81, December, 2006)

"This book presents a highly detailed and up-to-date report of the state of experimental embryology of the vertebrate inner ear. … Descriptive micrographs and illustrations are excellent and add much to the text. This book will be of great value to scientists and students working in the disciplines associated with development of the inner ear." (American Journal of Neuroradiology, Vol. 29, April, 2008)