Viral Membrane Proteins: Structure, Function, and Drug Design

  • Wolfgang B. Fischer

Part of the Protein Reviews book series (PRON, volume 1)

Table of contents

  1. Front Matter
    Pages i-xviii
  2. Membrane Proteins from Plant Viruses

    1. Front Matter
      Pages 1-1
    2. Michael J. Adams, John F. Antoniw
      Pages 3-19
    3. Anna Moroni, James Van Etten, Gerhard Thiel
      Pages 21-32
  3. Fusion Proteins

    1. Front Matter
      Pages 33-33
    2. Sergio G. Peisajovich, Yechiel Shai
      Pages 35-47
    3. L. Vaccaro, K. J. Cross, S. A. Wharton, J. J. Skehel, F. Fraternali
      Pages 65-75
  4. Viral Ion Channels/viroporins

    1. Front Matter
      Pages 77-77
    2. María Eugenia González, Luis Carrasco
      Pages 79-90
    3. Itamar Kass, Isaiah T. Arkin
      Pages 91-100
    4. Yajun Tang, Padmavati Venkataraman, Jared Knopman, Robert A. Lamb, Lawrence H. Pinto
      Pages 101-111
    5. S. J. Opella, S. H. Park, S. Lee, D. Jones, A. Nevzorov, M. Mesleh et al.
      Pages 147-163
    6. V. Lemaitre, C. G. Kim, D. Fischer, Y. H. Lam, A. Watts, W. B. Fischer
      Pages 187-205
    7. Peter W. Gage, Gary Ewart, Julian Melton, Anita Premkumar
      Pages 207-231
    8. M. A. Sanz, V. Madan, J. L. Nieva, Luis Carrasco
      Pages 233-244

About this book

Introduction

Protein Reviews, a new book series from Springer, covers all aspects of protein investigations including protein chemistry, sequence, 3-D structure, biological activity, proteomics, methodology, and many more new and emerging topics.

Volume 1: Viral Membrane Proteins: Structure, Function and Drug Design

Edited by Wolfgang B. Fischer

This volume, written by renowned leaders in the field, summarizes the current structural and functional knowledge of membrane proteins encoded by viruses while addressing questions about the proteins as potential drug targets.

Early praise for this volume:

"We all know that you can't treat viral disease with drugs.....That was what all physicians and scientists were taught for decades with conviction but without enough experiments. Fortunately, we were taught wrong: rationally designed drugs are available that work well against influenza as Garman and Laver describe so well (with the help of Wen Yang Wu) in a fascinating chapter of this book. In fact, viral membrane proteins have a range of functions of great medical and biological importance, not so surprisingly if one understands that membrane proteins control a wide range of function because they are gatekeepers for cells. Membrane proteins control entry into cells and viruses.

Viral Membrane Proteins" is a wonderful description of some of these proteins. The authors and editor are to be congratulated on producing much more than a collection of reviews and essays.

This book can help teach everyone that it is possible to treat viral disease with drugs that bind to membrane proteins. Knowing that, we can hope that more resources will be focused on finding other such drugs to the remaining scourges of mankind, at least those we do not produce ourselves."

- Robert S. Eisenberg, Rush University Medical Center, Chicago, IL

 

Keywords

HIV biochemistry enzymes infections membrane proteins protein proteins virus

Editors and affiliations

  • Wolfgang B. Fischer
    • 1
  1. 1.Department of BiochemistryUniversity of OxfordUK

Bibliographic information

  • DOI https://doi.org/10.1007/0-387-28146-0
  • Copyright Information Kluwer Academic/Plenum Publishers, New York 2005
  • Publisher Name Springer, Boston, MA
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-0-306-48495-7
  • Online ISBN 978-0-387-28146-9
  • About this book