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Incidence, Risk Factors, and Management of Infection Following Anterior Cruciate Ligament Reconstruction Surgery

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Abstract

Background

Infection after anterior cruciate ligament reconstruction surgery (ACLRS) is a rare complication. Although there are number of studies from various Caucasian population but only few studies are available from Asian population. The aim of the study is to assess the incidence, risk factors and, clinical outcome using our treatment protocol

Materials and Methods

Out of 1468 arthroscopic ACLRS, 26 patients with clinical suspicion of infection were critically analysed in terms of laboratory reports of arthrocentesis, erythrocyte sedimentation rate, C-reactive protein and risk factors such as the type of graft, gender, diabetes mellitus, smoking, intraarticular steroid injection, and obesity. At final followup, all these patients were evaluated using visual analog scale (VAS), Lysholm knee score, and Tegner activity level

Results

In nine patients, culture did not show any growth and they showed improvement with arthrocentesis and oral antibiotics. These patients were labeled as suffering from aseptic effusion. In the remaining 17 patients, there was no clinical improvement or instead worsening of symptoms after arthrocentesis and oral antibiotics. These patients were labeled as suffering from an infection and underwent surgical debridement along with administration of injectable antibiotics. The history of intraarticular steroid injection before ACLRS was a significant risk factor for developing infection (P = 0.001). At mean followup of 2.8 years, mean VAS improved to 1.18 ± 0.99 from 6.2 ± 2.3. The mean Lysholm knee score and Tegner’s activity level at the final followup were 79.2 ± 10.52 and 4.8 ± 2.30, respectively

Conclusion

The incidence of infection was 1.2% (17/1468). The step-ladder approach of differentiating between aseptic effusion and infection and accordingly, following a treatment protocol, i.e., oral antibiotics alone or surgical debridement along with injectable antibiotics or additional debridement of graft in refractory patients, yielded satisfactory results

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References

  1. Frank M, Schmucker U, David S, Matthes G, Ekkernkamp A, Seifert J, et al. Devastating femoral osteomyelitis after anterior cruciate ligament reconstruction. Knee Surg Sports Traumatol Arthrosc 2008;16:71–4.

    Article  CAS  Google Scholar 

  2. Judd D, Bottoni C, Kim D, Burke M, Hooker S. Infections following arthroscopic anterior cruciate ligament reconstruction. Arthroscopy 2006;22:375–84.

    Article  Google Scholar 

  3. McAllister DR, Parker RD, Cooper AE, Recht MP, Abate J. Outcomes of postoperative septic arthritis after anterior cruciate ligament reconstruction. Am J Sports Med 1999;27:562–70.

    Article  CAS  Google Scholar 

  4. Schollin-Borg M, Michaëlsson K, Rahme H. Presentation, outcome, and cause of septic arthritis after anterior cruciate ligament reconstruction: A case control study. Arthroscopy 2003;19:941–7.

    Article  Google Scholar 

  5. Van Tongel A, Stuyck J, Bellemans J, Vandenneucker H. Septic arthritis after arthroscopic anterior cruciate ligament reconstruction: A retrospective analysis of incidence, management and outcome. Am J Sports Med 2007;35:1059–63.

    Article  Google Scholar 

  6. Kuršumović K, Charalambous CP. Graft salvage following infected anterior cruciate ligament reconstruction: A systematic review and meta-analysis. Bone Joint J 2016;98-B:608–15.

    Article  Google Scholar 

  7. Wang C, Ao Y, Wang J, Hu Y, Cui G, Yu J, et al. Septic arthritis after arthroscopic anterior cruciate ligament reconstruction: A retrospective analysis of incidence, presentation, treatment, and cause. Arthroscopy 2009;25:243–9.

    Article  Google Scholar 

  8. Stucken C, Garras DN, Shaner JL, Cohen SB. Infections in anterior cruciate ligament reconstruction. Sports Health 2013;5:553–7.

    Article  Google Scholar 

  9. Brophy RH, Wright RW, Huston LJ, Nwosu SK; MOON Knee Group, Spindler KP, et al. Factors associated with infection following anterior cruciate ligament reconstruction. J Bone Joint Surg Am 2015;97:450–4.

    Article  Google Scholar 

  10. Huttunen R, Syrjänen J. Obesity and the risk and outcome of infection. Int J Obes (Lond) 2013;37:333–40.

    Article  CAS  Google Scholar 

  11. Kim SJ, Postigo R, Koo S, Kim JH. Infection after arthroscopic anterior cruciate ligament reconstruction. Orthopedics 2014;37:477–84.

    Article  Google Scholar 

  12. Nag HL, Neogi DS, Nataraj AR, Kumar VA, Yadav CS, Singh U, et al. Tubercular infection after arthroscopic anterior cruciate ligament reconstruction. Arthroscopy 2009;25:131–6.

    Article  Google Scholar 

  13. Plurad DS, Lustenberger T, Kilday P, Zhu J, Green DJ, Inaba K, et al. The association of race and survival from sepsis after injury. Am Surg 2010;76:43–7.

    PubMed  Google Scholar 

  14. Gupta R, Bahadur R, Malhotra A, Masih GD, Gupta P. Anterior cruciate ligament reconstruction using hamstring tendon autograft with preserved insertions. Arthrosc Tech 2016;5:e269–74.

    Article  Google Scholar 

  15. Lysholm J, Gillquist J. Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale. Am J Sports Med 1982;10:150–4.

    Article  CAS  Google Scholar 

  16. Tegner Y, Lysholm J. Rating systems in the evaluation of knee ligament injuries. Clin Orthop Relat Res 1985;198:43–9.

    Google Scholar 

  17. Mouzopoulos G, Fotopoulos VC, Tzurbakis M. Septic knee arthritis following ACL reconstruction: A systematic review. Knee Surg Sports Traumatol Arthrosc 2009;17:1033–42.

    Article  Google Scholar 

  18. Schulz AP, Götze S, Schmidt HG, Jürgens C, Faschingbauer M. Septic arthritis of the knee after anterior cruciate ligament surgery: A stage-adapted treatment regimen. Am J Sports Med 2007;35:1064–9.

    Article  Google Scholar 

  19. Maletis GB, Inacio MC, Reynolds S, Desmond JL, Maletis MM, Funahashi TT, et al. Incidence of postoperative anterior cruciate ligament reconstruction infections: Graft choice makes a difference. Am J Sports Med 2013;41:1780–5.

    Article  Google Scholar 

  20. Coutinho AE, Chapman KE. The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights. Mol Cell Endocrinol 2011;335:2–13.

    Article  CAS  Google Scholar 

  21. Papavasiliou AV, Isaac DL, Marimuthu R, Skyrme A, Armitage A. Infection in knee replacements after previous injection of intraarticular steroid. J Bone Joint Surg Br 2006;88:321–3.

    Article  CAS  Google Scholar 

  22. Schuster P, Schulz M, Immendoerfer M, Mayer P, Schlumberger M, Richter J, et al. Septic arthritis after arthroscopic anterior cruciate ligament reconstruction: Evaluation of an arthroscopic graft-retaining treatment protocol. Am J Sports Med 2015;43:3005–12.

    Article  Google Scholar 

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Correspondence to Ravi Gupta.

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Gupta, R., Sood, M., Malhotra, A. et al. Incidence, Risk Factors, and Management of Infection Following Anterior Cruciate Ligament Reconstruction Surgery. IJOO 52, 399–405 (2018). https://doi.org/10.4103/ortho.IJOrtho_379_17

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