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Abstract
Objective
To evaluate the effectiveness of using topical nasal steroids versus oral steroids in the treatment of otitis media with effusion (OME) in children.
Methods
One hundred (100) patients were included in the study, they were divided into two equal groups, group A received intranasal mometasone furoate spray once daily for 6 weeks, and group B received oral steroids in tapering doses for 6 weeks, plus systemic antibiotics, and nasal decongestants for both groups, tympanogram was done every 2 weeks for all patients.
Results
Highly significant improvement (P < 0.01) of OME regarding symtoms, signs, and tympanometric results, occurred in each group separately at the end of the study, with no significant difference (P > 0.05) in improvement between the two groups.
Conclusion
Both topical intranasal and oral steroids are effective medical therapy in the treatment of OME in children with no significant difference between the two methods.
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References
Stool SE, Berg AO, Berman S, et al. Otitis media with effusion in young children. Agency for Health Care Policy and Research. Clin Pract Guideline 1994; 12: 1–13.
Williamson IG, Dunleavey J, Bain J, Robinson D. The natural history of otitis media with effusion — a three-year study of the incidence and prevalence of abnormal tympanograms in four South West Hampshire infant and first schools. J Laryngol Otol 1994; 108: 930–934.
Rosenfeld RM, Kay D. Natural history of untreated otitis media. The laryngoscope. Lippincott Williams & Wilkins; 2003; 113: 1645–1657.
American Academy of Family Physicians, American Academy Of Otolaryngology-Head and Neck Surgery, American Academy of Pediatrics Subcommittee on Otitis Media with Effusion. Otitis media with effusion. Pediatrics 2004; 113:1412–1429.
Rosenfeld RM, Bluestone CD. Evidence-based otitis media. Hamilton, Canada: BC Decker Inc; 1999.
Cengel S, Akyol MU. The role of topical nasal steroids in the treatment of children with otitis media with effusion and/or adenoid hypertrophy. Int J Pediatr Otorhinolaryngol 2006; 70: 639–645.
Stool SE, Berg AO, Berman S, et al. Otitis media with effusion in children. Guideline Technical Report. No 12. AHCPR. Pub No.95-0621. Rockville, MD: US Department of Health and Human Services; 1994.
Zielhuis GA, Rach GH, Broek PV. Screening for otitis media with effusion in preschool children. Lancet 1989; 1: 311–314.
Casselbrant ML, Brostoff LM, Cantekin EI, Flaherty MR, Doyle WJ, Bluestone CD, Fria TJ. Otitis media with effusion in preschool children. Laryngoscope 1985; 95: 428–436.
Haggard M, Hughes E. Screening children’s hearing: a review of the literature and implications of otitis media. London, UK: HMSO; 1991.
Petrou S, Dakin H, Abangma G, Benge S, Williamson I. Cost-utility analysis of topical intranasal steroids for otitis media with effusion based on evidence from the GNOMETrial. Value Health 2010; 13: 543–551.
Poliakova SD, Popova EA. Effectiveness criteria for the topical application of glucocorticosteroids to the treatment of exudative otitis media associated with allergic rhinitis. Arch Otolaryngol Head Neck Surg 2011; 137: 449–455.
Goldbart AD, Veling MC, Goldman JL, Li RC, Brittian KR, Gozal D. Glucocorticoid receptor subunit expression in adenotonsillar tissue of children with obstructive sleep apnea. Pediatr Res 2005; 57: 232–236.
Laliberte F, Laliberte MF, Lecart S, Bousquet J, Klossec JM, Mounedji N. Clinical and pathologic methods to assess the long-term safety of nasal corticosteroids. French Triamcinolone Acetonide Study Group. Allergy 2000; 55: 718–722.
Szefler SJ. Pharmacokinetics of intranasal corticosteroids. J Allergy Clin Immunol 2001; 108: 26–31.
Williamson I, Benge S, Barton S, Petrou S, Letley L, Fasey N, et al. Topical intranasal corticosteroids in 4–11 year old children with persistent bilateral otitis media with effusion in primary care: double blind randomised placebo controlled trial. BMJ 2009; 339:b4984.
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Anwar, M., Abdel-Aziz, M., Nassar, A. et al. A comparative study of the efficacy of topical nasal steroids versus systemic steroids in the treatment of otitis media with effusion in children. Egypt J Otolaryngol 31, 208–212 (2015). https://doi.org/10.4103/1012-5574.168210
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DOI: https://doi.org/10.4103/1012-5574.168210