Skip to main content

Advertisement

Log in

Midterm results of 36 mm metal-on-metal total hip arthroplasty

  • Original Article
  • Published:
Indian Journal of Orthopaedics Aims and scope Submit manuscript

Abstract

Background

Despite the many perceived benefits of metal-on-metal (MoM) articulation in total hip arthroplasty (THA), there have been growing concerns about metallosis and adverse reaction to metal debris (ARMD). Analysis of size 36 mm MoM articulation THAs is presented. These patients were evaluated for patient characteristics, relationship between blood metal ions levels and the inclination as well as the version of acetabular component, cumulative survival probability at final followup and functional outcome at final followup.

Materials and Methods

288, size 36 mm MoM THAs implanted in 269 patients at our institution from 2004 to 2010 were included in this retrospective study. These patients were assessed clinically for hip symptoms, perioperative complications and causes of revision arthroplasty were analysed. Biochemically, blood cobalt and chromium metal ions level were recorded and measurements of acetabular inclination and version were examined. Radiological evaluation utilizing Metal Artefact Reduction Sequence (MARS) MRI was undertaken and implant cumulative survivorship was evaluated.

Results

The mean followup was 5 years (range 2–7 years), mean age was 73 years and the mean Oxford hip score was 36.9 (range 5–48). Revision arthroplasty was executed in 20 (7.4%) patients, of which 15 patients underwent single-stage revision THA. The causes of revision arthroplasty were: ARMD changes in 6 (2.2%) patients, infection in 5 (1.9%) patients and aseptic loosening in 5 (1.9%) patients. Three (1.1%) patients had their hips revised for instability, 1 (0.3%) for raised blood metal ions levels. The implant cumulative survival rate, with revision for any reason, was 68.9% at 7 years.

Conclusions

Although medium-sized MoM THA with a 36 mm head has a marginally better survivorship at midterm followup, compared to larger size head MoM articulating THA, our findings nonetheless are still worryingly poor in comparison to what has been quoted in the literature. Furthermore, ARMD-related revision remains the predominant cause of failure in this cohort with medium-sized MoM articulation. No correlation was found between blood metal ions levels and the inclination as well as the version of acetabular component.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Cohen D. How safe are metal-on-metal hip implants? BMJ 2012;344:e1410.

    Article  Google Scholar 

  2. Quesada MJ, Marker DR, Mont MA. Metal-on-metal hip resurfacing: Advantages and disadvantages. J Arthroplasty 2008;23 7 Suppl:69–73.

    Article  Google Scholar 

  3. Australian Orthopaedic Association National Joint Replacement R. Annual Report/Australian Orthopaedic Association, National Joint Replacement Registry; 2013. Available from: http://www.nla.gov.au/nla.cat-vn2616774. (Date last accessed 15/08/2014)

    Google Scholar 

  4. 7th Annual Report England and Wales: National Joint Registry; 2010.

  5. Garellick G, Kärrholm J, Rogmark, C, Herberts, P. The Swedish Hip Arthroplasty Register Annual Report Sweden: The Swedish Hip Arthroplasty Register; 2010.

    Google Scholar 

  6. Langton DJ, Jameson SS, Joyce TJ, Hallab NJ, Natu S, Nargol AV. Early failure of metal-on-metal bearings in hip resurfacing and large-diameter total hip replacement: A consequence of excess wear. J Bone Joint Surg Br 2010;92:38–46.

    Article  CAS  Google Scholar 

  7. Ollivere B, Darrah C, Barker T, Nolan J, Porteous MJ. Early clinical failure of the Birmingham metal-on-metal hip resurfacing is associated with metallosis and soft-tissue necrosis. J Bone Joint Surg Br 2009;91:1025–30.

    Article  CAS  Google Scholar 

  8. Willert HG, Buchhorn GH, Fayyazi A, Flury R, Windler M, Köster G, et al. Metal-on-metal bearings and hypersensitivity in patients with artificial hip joints. A clinical and histomorphological study. J Bone Joint Surg Am 2005;87:28–36.

    Article  Google Scholar 

  9. Canadian Arthroplasty Society. The Canadian Arthroplasty Society’s experience with hip resurfacing arthroplasty. An analysis of 2773 hips. Bone Joint J 2013;95-B:1045–51.

    Google Scholar 

  10. Ebreo D, Bell PJ, Arshad H, Donell ST, Toms A, Nolan JF. Serial magnetic resonance imaging of metal-on-metal total hip replacements. Follow-up of a cohort of 28 mm Ultima TPS THRs. Bone Joint J 2013;95-B:1035–9.

    Google Scholar 

  11. Agency. MaHpR. Medical Device Alert: All Metal-On-Metal (MoM) Hip Replacements (MDA/2010/033). Medicines and Healthcare Products Regulatory Agency; 2012.

    Google Scholar 

  12. Keegan GM, Learmonth ID, Case CP. Orthopaedic metals and their potential toxicity in the arthroplasty patient: A review of current knowledge and future strategies. J Bone Joint Surg Br 2007;89:567–73.

    Article  CAS  Google Scholar 

  13. De Haan R, Pattyn C, Gill HS, Murray DW, Campbell PA, De Smet K. Correlation between inclination of the acetabular component and metal ion levels in metal-on-metal hip resurfacing replacement. J Bone Joint Surg Br 2008;90:1291–7.

    Article  Google Scholar 

  14. Mai MC, Milbrandt JC, Hulsen J, Allan DG. Acetabular cup malalignment after total hip resurfacing arthroplasty: A case for elective revision? Orthopedics 2009;32:853.

    PubMed  Google Scholar 

  15. Hart AJ, Buddhdev P, Winship P, Faria N, Powell JJ, Skinner JA. Cup inclination angle of greater than 50 degrees increases whole blood concentrations of cobalt and chromium ions after metal-on-metal hip resurfacing. Hip Int 2008;18:212–9.

    Article  CAS  Google Scholar 

  16. Hart AJ, Skinner JA, Henckel J, Sampson B, Gordon F. Insufficient acetabular version increases blood metal ion levels after metal-on-metal hip resurfacing. Clin Orthop Relat Res 2011;469:2590–7.

    Article  Google Scholar 

  17. Nicolli A, Bisinella G, Padovani G, Vitella A, Chiara F, Trevisan A. Predictivity and fate of metal ion release from metal-on-metal total hip prostheses. J Arthroplasty 2014;29:1763–7.

    Article  Google Scholar 

  18. Mellon SJ, Grammatopoulos G, Andersen MS, Pandit HG, Gill HS, Murray DW. Optimal acetabular component orientation estimated using edge-loading and impingement risk in patients with metal-on-metal hip resurfacing arthroplasty. J Biomech 2015;48:318–23.

    Article  Google Scholar 

  19. Langton DJ, Jameson SS, Joyce TJ, Gandhi JN, Sidaginamale R, Mereddy P, et al. Accelerating failure rate of the ASR total hip replacement. J Bone Joint Surg Br 2011;93:1011–6.

    Article  CAS  Google Scholar 

  20. Smith AJ, Dieppe P, Vernon K, Porter M, Blom AW, National Joint Registry of England and Wales. Failure rates of stemmed metal-on-metal hip replacements: Analysis of data from the National Joint Registry of England and Wales. Lancet 2012;379:1199–204.

    Article  Google Scholar 

  21. Lehil MS, Bozic KJ. Trends in total hip arthroplasty implant utilization in the United States. J Arthroplasty 2014;29:1915–8.

    Article  Google Scholar 

  22. Hosman AH, van der Mei HC, Bulstra SK, Busscher HJ, Neut D. Effects of metal-on-metal wear on the host immune system and infection in hip arthroplasty. Acta Orthop 2010;81:526–34.

    Article  Google Scholar 

  23. Daou S, El Chemaly A, Christofilopoulos P, Bernard L, Hoffmeyer P, Demaurex N. The potential role of cobalt ions released from metal prosthesis on the inhibition of Hv1 proton channels and the decrease in Staphyloccocus epidermidis killing by human neutrophils. Biomaterials 2011;32:1769–77.

    Article  CAS  Google Scholar 

  24. Hallab N, Merritt K, Jacobs JJ. Metal sensitivity in patients with orthopaedic implants. J Bone Joint Surg Am 2001;83-A: 428–36.

    Article  Google Scholar 

  25. Martin SF. T lymphocyte-mediated immune responses to chemical haptens and metal ions: Implications for allergic and autoimmune disease. Int Arch Allergy Immunol 2004;134:186–98.

    Article  CAS  Google Scholar 

  26. Campbell P, Ebramzadeh E, Nelson S, Takamura K, De Smet K, Amstutz HC. Histological features of pseudotumor-like tissues from metal-on-metal hips. Clin Orthop Relat Res 2010;468:2321–7.

    Article  Google Scholar 

  27. Bolland BJ, Culliford DJ, Langton DJ, Millington JP, Arden NK, Latham JM. High failure rates with a large-diameter hybrid metal-on-metal total hip replacement: Clinical, radiological and retrieval analysis. J Bone Joint Surg Br 2011;93:608–15.

    Article  CAS  Google Scholar 

  28. Molli RG, Lombardi AV Jr, Berend KR, Adams JB, Sneller MA. Metal-on-metal vs metal-on-improved polyethylene bearings in total hip arthroplasty. J Arthroplasty 2011;26 6 Suppl: 8–13.

    Article  Google Scholar 

  29. Haddad FS, Thakrar RR, Hart AJ, Skinner JA, Nargol AV, Nolan JF, et al. Metal-on-metal bearings: The evidence so far. J Bone Joint Surg Br 2011;93:572–9.

    Article  CAS  Google Scholar 

  30. Glyn-Jones S, Pandit H, Kwon YM, Doll H, Gill HS, Murray DW. Risk factors for inflammatory pseudotumour formation following hip resurfacing. J Bone Joint Surg Br 2009;91:1566–74.

    Article  CAS  Google Scholar 

  31. Dawson J, Fitzpatrick R, Carr A, Murray D. Questionnaire on the perceptions of patients about total hip replacement. J Bone Joint Surg Br 1996;78:185–90.

    Article  CAS  Google Scholar 

  32. Hosny HA, Srinivasan SC, Keenan J, Fekry H. Midterm results with Birmingham Hip Resurfacing/Synergy stem modular metal-on-metal total hip arthroplasty. Acta Orthop Belg 2013;79:386–91.

    Google Scholar 

  33. Stafford GH, Islam SU, Witt JD. Early to mid-term results of ceramic-on-ceramic total hip replacement: Analysis of bearing-surface-related complications. J Bone Joint Surg Br 2011;93:1017–20.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hawar Akrawi.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Akrawi, H., Hossain, F.S., Niculescu, S. et al. Midterm results of 36 mm metal-on-metal total hip arthroplasty. IJOO 50, 256–262 (2016). https://doi.org/10.4103/0019-5413.181786

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.4103/0019-5413.181786

Key words

MeSH terms

Navigation