Skip to main content

Advertisement

Log in

Neonatal Candida arthritis

  • Case Report
  • Published:
Indian Journal of Orthopaedics Aims and scope Submit manuscript

Abstract

Fungal arthritis is an uncommon yet serious disorder in the newborn. Delay in diagnosis and management can lead to significant morbidity. We report our experience with management of two such cases. Two preterm neonates with multifocal arthritis caused by Candida were studied. Diagnosis was made by clinical examination, laboratory investigations, radiological investigations and culture. Both were treated by aspiration, arthrotomy and antifungal therapy. One patient recovered fully from the infection while the other had growth disturbances resulting in limb length inequality at recent followup. Prompt and expeditious evacuation of pus from joints and antifungal therapy is imperative for treatment. Associated osteomyelitis leads to further difficulty in treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Noyes FR, McCabe JD, Fekety FR Jr. Acute Candida arthritis. Report of a case and use of amphotericin B. Acute Candida arthritis 1973;55:169–76.

    CAS  Google Scholar 

  2. Cuéllar ML, Silveira LH, Espinoza LR. Fungal arthritis. Ann Rheum Dis 1992;51:690–7.

    Article  Google Scholar 

  3. Svirsky-Fein S, Langer L, Milbauer B, Khermosh O, Rubinstein E. Neonatal osteomyelitis caused by Candida tropicalis. Report of two cases and review of the literature. Neonatal osteomyelitis caused by Candida tropicalis 1979;61:455–9.

    CAS  Google Scholar 

  4. Herring JA. In: Herring JA, editor. Tachdijan’s Paediatric Orthopaedics. 3rd ed. Philadelphia: WB Saunders Co.; 2002. p. 1841–77.

  5. Deshpande SS, Taral N, Modi N, Singrakhia M. Changing epidemiology of neonatal septic arthritis. J Orthop Surg (Hong Kong) 2004;12:10–3.

    Article  CAS  Google Scholar 

  6. Toopey WH. Candidiasis in the newborn. Intensive care Nursery House Staff Manual. 8th ed. UCSF Medical centre Manual, California. 2003. p. 128–9.

    Google Scholar 

  7. Stamos JK, Rowley AH. Candidemia in a pediatric population. Clin Infect Dis 1995;20:571–5.

    Article  CAS  Google Scholar 

  8. Lambertus M, Thordarson D, Goetz MB. Fungal prosthetic arthritis: Presentation of two cases and review of the literature. Rev Infect Dis 1988;10:1038–43.

    Article  CAS  Google Scholar 

  9. Ciftdemir NA. Fungal septic arthritis in the newborn. Turk Arch Pediatr 2011;46:92–93.

    Article  Google Scholar 

  10. Stoll BJ, Gordon T, Korones SB, Shankaran S, Tyson JE, Bauer CR, et al. Late-onset sepsis in very low birth weight neonates: A report from the National Institute of Child Health and Human Development Neonatal Research Network. J Pediatr 1996;129:63–71.

    Article  CAS  Google Scholar 

  11. Hsieh WB, Leung C. Candidal arthritis after complete treatment of systemic candidiasis. J Chin Med Assoc 2005;68:191–4.

    Article  Google Scholar 

  12. Narain S. Neonatal systemic candidiasis in a tertiary care centre. Indian J Med Microbiol 2003;21:56–8.

    CAS  PubMed  Google Scholar 

  13. Fisher F, Cook NB. Fundamentals of Diagnostic Mycology. 1st ed. Philadelphia: WB Saunders Company; 1998. p. 200.

    Google Scholar 

  14. Lyon RM, Evanich JD. Culture-negative septic arthritis in children. J Pediatr Orthop 1999;19:655–9.

    CAS  PubMed  Google Scholar 

  15. Ho NK, Low YP, See HF. Septic arthritis in the newborn: A 17 years’ clinical experience. Singapore Med J 1989;30:356–8.

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Saurabh Sharma.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sharma, S., Gangwal, K. Neonatal Candida arthritis. IJOO 48, 339–342 (2014). https://doi.org/10.4103/0019-5413.132533

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.4103/0019-5413.132533

Key words

Navigation