Abstract
30 year old female patient with giant cell tumor of the distal tibia initially treated at a peripheral nononcological center by curettage and autologous bone grafting from the ipsilateral iliac crest reported to us with local recurrence and an implantation giant cell tumor at the graft harvesting site which required extensive surgeries at both sites. The risk of iatrogenic direct implantation of tumor, often attributable to inadequate surgical planning or poor surgical techniques, and the steps to prevent such complication is reported here.
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Heck RK. Benign/aggressive tumors of bone. In: Canale ST, Beaty JH, editors. Campbell’s operative orthopaedics. 11th ed. Philadephia: Mosby Elsevier; 2008. p. 883–900.
Rock MG, Pritchard DJ, Unni KK. Metastases from histologically benign giant-cell tumor of bone. J Bone Joint Surg Am 1984;66:269–74.
Sladden RA. Intravascular osteoclasts. J Bone Joint Surg Br 1957;39:346–57.
Jaffe HL. Giant cell tumour (osteoclastoma) of bone: Its pathologic delimitation and the inherent clinical implications. Ann R Coll surg Engl 1953;13:343–55.
Dominkus M, Ruggieri P, Bertoni F, Briccoli A, Picci P, Rocca M, et al. Histologically verified lung metastases in benign giant cell tumours-14 cases from a single institution. Int Orthop 2006;30:499–504.
Rosenberg AE. Bone, joints, and soft tissue tumors. In: Kumar V, Abbas AK, Fausto N, editors. Pathologic basis of disease. Philadelphia: Saunders; 2004. p. 1273–325.
Joynt GH, Ortved WE. The accidental operative transplantation of benign giant cell tumor. Ann Surg 1948;127:1232–9.
Ofluoglu O, Donthineni R. Iatrogenic seeding of a giant cell tumor of the patella to the proximal tibia. Clin Orthop Relat Res 2007;465:260–4.
Sung HW, Kuo DP, Shu WP, Chai YB, Liu CC, Li SM. Giantcell tumor of bone: Analysis of two hundred and eight cases in Chinese patients. J Bone Joint Surg Am 1982;64:755–-61.
Cole GW Jr, Sindelar WF. Iatrogenic transplantation of osteosarcoma. South Med J 1995;88:485–8.
Ebelin M, Missenard G, Nordin JY. Iatrogenic tumor metastasis to the pelvis after treatment for hand osteosarcoma. A case report. Chir Main 2000;19:272–5.
Yip KM, Lin J, Kumta SM. A pelvic osteosarcoma with metastasis to the donor site of the bone graft. A case report. Int Orthop 1996;20:389–91.
Dias RG, Abudu A, Carter SR, Grimer RJ, Tillman RM. Tumour transfer to bone graft donor site: A case report and review of the literature of the mechanism of seeding. Sarcoma 2000;4:57–-9.
Flook D, Horgan K, Taylor BA, Hughes LE. Surgery for malignant melanoma: From which limb should the graft be taken? Br J Surg 1986;73:793–5.
Cunha-Gomes D, Prasad R, Bhathena HM, Kavarana NM. Tumor implantation at the flap donor site: A case report. Acta Chir Plast 1999;41:75–6.
Ferguson PC, Sommerville S, Grimer RJ. Possible metastasis of osteosarcoma to a remote biopsy site: A case report. Clin Orthop Relat Res 2004;424:216–20.
Ryall C. Cancer infection and cancer recurrences: A danger to avoid in cancer operations. Lancet 1907;2:1311–16.
Fisher B, Fisher ER, Feduska N. Trauma and the localization of tumor cells. Cancer 1967;20:23–30.
Murthy SM, Goldschmidt RA, Rao LN, Ammirati M, Buchmann T, Scanlon EF. The influence of surgical trauma on experimental metastasis. Cancer 1989;64:2035–44.
Alexander JW, Altemeier WA. Susceptibility of injured tissues to hematogenous metastases: An experimental study. Ann Surg 1964;159:933–44.
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Kundu, Z.S., Gupta, V., Sangwan, S.S. et al. Iatrogenic giant cell tumor at bone graft harvesting site. IJOO 47, 107–110 (2013). https://doi.org/10.4103/0019-5413.106936
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DOI: https://doi.org/10.4103/0019-5413.106936