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Advances in boron neutron capture therapy (BNCT) at kyoto university - From reactor-based BNCT to accelerator-based BNCT

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Abstract

At the Kyoto University Research Reactor Institute (KURRI), a clinical study of boron neutron capture therapy (BNCT) using a neutron irradiation facility installed at the research nuclear reactor has been regularly performed since February 1990. As of November 2014, 510 clinical irradiations were carried out using the reactor-based system. The world’s first accelerator-based neutron irradiation system for BNCT clinical irradiation was completed at this institute in early 2009, and the clinical trial using this system was started in 2012. A shift of BCNT from special particle therapy to a general one is now in progress. To promote and support this shift, improvements to the irradiation system, as well as its preparation, and improvements in the physical engineering and the medical physics processes, such as dosimetry systems and quality assurance programs, must be considered. The recent advances in BNCT at KURRI are reported here with a focus on physical engineering and medical physics topics.

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Authors and Affiliations

  1. Kyoto University Research Reactor Institute, Asashiro-nishi 2-1010, Kumatori-cho, Sennan-gun, Osaka, 590-0494, Japan

    Yoshinori Sakurai, Hiroki Tanaka, Takushi Takata, Nozomi Fujimoto, Minoru Suzuki, Shinichiro Masunaga, Yuko Kinashi, Natsuko Kondo, Masaru Narabayashi, Yosuke Nakagawa, Tsubasa Watanabe, Koji Ono & Akira Maruhashi

Authors
  1. Yoshinori Sakurai
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  2. Hiroki Tanaka
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  3. Takushi Takata
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  4. Nozomi Fujimoto
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  5. Minoru Suzuki
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  6. Shinichiro Masunaga
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  7. Yuko Kinashi
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  8. Natsuko Kondo
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  9. Masaru Narabayashi
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  10. Yosuke Nakagawa
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  11. Tsubasa Watanabe
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  12. Koji Ono
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  13. Akira Maruhashi
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Correspondence to Yoshinori Sakurai.

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Sakurai, Y., Tanaka, H., Takata, T. et al. Advances in boron neutron capture therapy (BNCT) at kyoto university - From reactor-based BNCT to accelerator-based BNCT. Journal of the Korean Physical Society 67, 76–81 (2015). https://doi.org/10.3938/jkps.67.76

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  • DOI: https://doi.org/10.3938/jkps.67.76

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