Skip to main content
SpringerLink
Log in

Design optimization of a small-animal SPECT system using LGSO continuous crystals and micro parallel-hole collimators

  • Published:
Journal of the Korean Physical Society Aims and scope Submit manuscript

Abstract

A small-animal single photon emission computed tomography (SPECT) system having compact size and low cost was designed using monolithic LGSO scintillation crystals and micro parallel-hole collimators through Monte Carlo simulations. A spatial resolution of ~1 mm and a sensitivity of ~100 cps/MBq were achieved with a four-head SPECT system. A hot rod with a diameter of 1.0 mm was resolved in the SPECT image of the ultra-micro hot spot phantom. Using a thin monolithic crystal and micro collimator, we achieved high spatial resolution and high sensitivity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. S. Y. Park, H. Yoon, N. Lee, J. K. Oh, I. R. Yoo, S. H. Kim and Y. A. Chung, Nucl. Med. Mol. Imaging. 48, 272 (2014).

    Article  Google Scholar 

  2. T. K. Lee et al., Nucl. Med. Mol. Imaging. 48, 225 (2014).

    Article  Google Scholar 

  3. J. R. Stickel and S. R. Cherry, Phys. Med. Biol. 50, 179 (2005).

    Article  MATH  Google Scholar 

  4. M. Rodr`iguez-Villafuerte, Y. Yang and S. R. Cherry, Phys. Med. 30, 76 (2014).

    Article  Google Scholar 

  5. J. Brodfuehrer et al., Pharm. Res. 31, 635 (2014).

    Article  Google Scholar 

  6. K. H. Yu, H. Yoon, M. G. Song, D. S. Lee and J-K. Chung, Nucl. Med. Mol. Imaging 46, 239 (2012).

    Article  MATH  Google Scholar 

  7. F. Van der Have, B. Vastenhouw, R. M. Ramakers, W. Branderhorst, J. O. Krah, C. Ji, S. G. Staelens and F. J. Beekman, J. Nucl. Med. 50, 599 (2009).

    Article  Google Scholar 

  8. S. Shokouhi, S. D. Metzler, D. W. Wilson and T. E. Peterson. Phys. Med. Biol. 54, 207 (2009).

    Article  Google Scholar 

  9. S. Staelens, D. Strul, G. Santin, S. Vandenberghe, M. Koole, Y. D’Asseler, I. Lemahieu and R. Van de Walle, Phys. Med. Biol. 48, 3021 (2003).

    Article  Google Scholar 

  10. S. Lee, J. Gregor and D. Osborne, Mol. Imaging. 12, 1 (2013).

    MATH  Google Scholar 

  11. S. J. Hong, S. I. Kwon, M. Ito, G. S. Lee, K-S. Sim, K-S. Park, J. T. Rhee and J. S. Lee, IEEE Trans. Nucl. Sci. 55, 912 (2008).

    Article  ADS  MATH  Google Scholar 

  12. R. Yao, T. Ma and Y. Shao, Phys. Med. Biol. 53, 4399 (2008).

    Article  Google Scholar 

  13. M. E. Myronakis and D. G. Darambara, Med. Phys. 38, 455 (2011).

    Article  Google Scholar 

  14. B. S. McDonald, S. Shokouhi, H. H. Barrett and T. E. Peterson, Nucl. Instrum. Meth. Phys. Res. A 579, 196 (2007).

    Article  ADS  Google Scholar 

  15. H. Choi, W. W. Lee, Y. So, S. Ha, S-S. Byun and S. E. Kim, Nucl. Med. Mol. Imaging 48, 262 (2014).

    Article  Google Scholar 

  16. M. Lipowska, J. Klenc, R. D. Folks and A. T. Taylor, Nucl. Med. Mol. Imaging 48, 216 (2014).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Center for Ionizing Radiation, Division of Metrology for Quality of Life, Korea Research Institute of Standards and Science, Daejeon, 305-340, Korea

    Joong Hyun Kim

  2. Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, 110-744, Korea

    Mikiko Ito & Soo Mee Kim

  3. Department of Radiological Science, Eulji University, Seongnam, 461-713, Korea

    Seong Jong Hong

  4. Department of Nuclear Medicine and Biomedical Sciences and Institute of Radiation Medicine, Medical Research Center, Seoul National University College of Medicine, Seoul, 110-744, Korea

    Jae Sung Lee

Authors
  1. Joong Hyun Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mikiko Ito
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Soo Mee Kim
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Seong Jong Hong
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Jae Sung Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Jae Sung Lee.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kim, J.H., Ito, M., Kim, S.M. et al. Design optimization of a small-animal SPECT system using LGSO continuous crystals and micro parallel-hole collimators. Journal of the Korean Physical Society 67, 224–231 (2015). https://doi.org/10.3938/jkps.67.224

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.3938/jkps.67.224

Keywords

Search

Navigation