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Study on the effects of gadolinium-based MRI contrast medium on X-ray scanning

Abstract

Gadolinium has a higher atomic mass (64) than iodine (53). The K-edge absorption energy of gadolinium is 50.2 keV, which is in the absorbed wavelength range of the X-rays used by a CT scanner, suggesting that it has a high X-ray absorption ability. This study examined the effects of a gadolinium-based MRI contrast medium on the quality (mAs) and the quality (kVp) of radiation during a X-ray scan. A contrast medium phantom was manufactured after diluting the contrast medium to various concentrations. A CT scanner (Siemens, Somatom Senation 64, Germany) was used to obtain images by changing the quality of radiation from 80 kVp to 100, 120, and 140 kVp. At a constant quality of radiation of 120 kVp, the mAs was changed from 100 mAs to 200 and 300 mAs and images were obtained under each condition. The Hounsfield units (HUs) in a test tube were measured for analysis and comparison. The contrast enhancement by the contrast medium for CT scanning was 100% at a tube voltage of 80 kVp. The contrast enhancements at 100 kVp, 120 kVp, and 140 kVp were 93.8%, 87.7%, and 69.5%, respectively. In addition, although the quantity increased a fixed tube voltage, the HU of the test tube remained relatively constant, indicating that the absorption of the contrast medium had little association with the quantity of X-rays but had some correlation with the quality of radiation. A tube voltage of 80 kVp or lower is recommended when a MRI contrast medium is used CT scanning. When MRI scanning and X-ray scanning are conducted together, X-ray scanning should be performed first or after sufficient gadolinium contrast medium has been excreted.

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References

  1. [1]

    G. N. Holland, R. C. Hawkes and W. S. Moore, J. Comput. Assist. Tomo. 4, 429 (1980).

    Article  Google Scholar 

  2. [2]

    R. W. Katzberg, Radiology 235, 752 (2005).

    Article  Google Scholar 

  3. [3]

    J. O. Hoppe, A. A. Larsen and F. Coulston, J. Pharmacol. Exp. Ther. 116, 394 (1956).

    Google Scholar 

  4. [4]

    D. Meyer, M. Schaefer and B. Bonnemain, Invest. Radiol. 23(Suppl 1), 232 (1988).

    Google Scholar 

  5. [5]

    H. Katayama, K. Yamaguchi, T. Kozuka, T. Takashima, P. Seez and K. Matuura, Radiology 175, 621 (1990).

    Google Scholar 

  6. [6]

    K. L. Nelson, L. M. Gifford, C. Lauber-Huber, C. A. Gross and T. A. Lasser, Radiology 196, 439 (1995).

    Google Scholar 

  7. [7]

    D. S. Gierada and K. T. Bae, Radiology 210, 829 (1999).

    Google Scholar 

  8. [8]

    U. Nyman, B. Elmstahl, P. Leander, M. Nilsson, K. Golman and T. Almen, Radiology 223, 311 (2002).

    Article  Google Scholar 

  9. [9]

    W. Luboldt, E. M. De Santis, A. von Smekal and M. Reiser, Invest. Radiol. 32, 690 (1997).

    Article  Google Scholar 

  10. [10]

    H. A. Goldstein, F. K. Kashanian, R. F. Blumetti, W. L. Holyoak, F. P. Hugo and D. M. Blumenfield, Radiology 174, 17 (1990).

    Google Scholar 

  11. [11]

    H. P. Niendorf, J. C. Dinger, J. Haustein, I. Cornelius, A. Alhassan and W. Clauss, Eur. J. Radiol. 13, 15 (1991).

    Article  Google Scholar 

  12. [12]

    M. R. Prince, C. Arnoldus and J. K. Frisoli, J. Magn. Reson. Imaging 6, 162 (1996).

    Article  Google Scholar 

  13. [13]

    D. B. Spring, M. A. Bettmann and H. E. Barkan, Radiology 204, 325 (1997).

    Google Scholar 

  14. [14]

    Y. Kinno, K. Odagiri, K. Andoh, Y. Itoh and K. Tarao, Am. J. Roentgenol. 160, 1293 (1993).

    Google Scholar 

  15. [15]

    M. Ishida, H. Sakuma, S. Murashima, J. Nishida, M. Senga, S. Kobayasi, K. Takeda and N. Kata, J. Magn. Reson. Imaging 29, 205 (2009).

    Article  Google Scholar 

  16. [16]

    T. Albrecht and P. Dawson, Br. J. Radiol. 73, 878 (2000).

    Google Scholar 

  17. [17]

    H. S. Thomsen, S. K. Morcos and P. Dawson, Clin. Radiol. 61, 905 (2006).

    Article  Google Scholar 

  18. [18]

    F. J. Palmer, Australas. Radiol. 32, 426 (1988).

    Article  Google Scholar 

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Correspondence to Woon-Kwan Chung.

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Yu, SM., Park, Y., Dong, KR. et al. Study on the effects of gadolinium-based MRI contrast medium on X-ray scanning. Journal of the Korean Physical Society 60, 142–148 (2012). https://doi.org/10.3938/jkps.60.142

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Keywords

  • Gadolinium
  • K-edge
  • Hounsfield unit
  • MRI