Abstract
One secoiridoid glycoside was isolated from the EtOAc-soluble fraction of flowers of Osmanthus fragrans var. aurantiacus by repeated silica gel, octadecyl silica gel (ODS) and Sephadex LH-20 column chromatographies. It was identified as (8E)-ligstroside based on spectroscopic methods including NMR and MS. This compound has been first isolated from Osmanthus fragrans var. aurantiacus, and showed BACE1 inhibition activity.
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Lee, DG., Choi, JS., Yeon, SW. et al. Secoiridoid glycoside from the flowers of Osmanthus fragrans var. aurantiacus makino inhibited the activity of β-secretase. J. Korean Soc. Appl. Biol. Chem. 53, 371–374 (2010). https://doi.org/10.3839/jksabc.2010.057
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DOI: https://doi.org/10.3839/jksabc.2010.057