Abstract
Three experiments examined inhibitory learning in rats, using Pavlovian and differential inhibitory eyeblink conditioning procedures. Experiment 1 was designed to compare summation and retardation effects following Pavlovian conditioned inhibition (A1/XA) or differential inhibition (A1/X) training using auditory and visual conditioned stimuli (CSs). After ten 100-trial sessions of training, both Pavlovian conditioned inhibition and differential inhibition produced a retardation effect. However, a summation effect was obtained only for rats given Pavlovian conditioned inhibition training. Experiment 2 showed that increasing differential inhibition training to twenty 100-trial sessions produced summation and retardation effects. In Experiment 3, rats were trained with either ten or twenty 100-trial sessions of intramodal inhibitory training with two tone CSs (2 kHz vs. 8 kHz). Summation and retardation effects were obtained after only 20 sessions of differential conditioning. The findings indicate that extensive training is needed to establish conditioned inhibition with intermodal or intramodal differential conditioning.
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Campolattaro, M. M., & Freeman, J. H. (2006). Perirhinal cortex lesions impair feature-negative discrimination. Neurobiology of Learning & Memory, 86, 205–213.
Couvillon, P. A., Ablan, C. D., & Bitterman, M. E. (1999). Exploratory studies of inhibitory conditioning in honeybees (Apis mellifera). Journal of Experimental Psychology: Animal Behavior Processes, 25, 103–112.
Freeman, J. H., Jr., Halverson, H. E., & Poremba, A. (2005). Differential effects of cerebellar inactivation on eyeblink conditioned excitation and inhibition. Journal of Neuroscience, 25, 889–895.
Freeman, J. H., Jr., & Nicholson, D. A. (1999). Neuronal activity in the cerebellar interpositus and lateral pontine nuclei during inhibitory classical conditioning of the eyeblink response. Brain Research, 833, 225–233.
Jones, D., & Gonzalez-Lima, F. (2001). Associative effects of Pavlovian differential inhibition of behaviour. European Journal of Neuroscience, 14, 1915–1927.
Kehoe, E. J. (1988). A layered network model of associative learning: Learning to learn and configuration. Psychological Review, 95, 411–433.
Kehoe, E. J., Morrow, L. D., & Holt, P. E. (1984). General transfer across sensory modalities survives reductions in the original conditioned reflex in the rabbit. Learning & Behavior, 12, 129–136.
Mahoney, W. J., Kwaterski, S. E., & Moore, J. W. (1975). Conditioned inhibition of the rabbits nictitating membrane response as a function of CS-US interval. Bulletin of the Psychonomic Society, 5, 177–179.
Nicholson, D. A., & Freeman, J. H., Jr. (2002). Neuronal correlates of conditioned inhibition of the eyeblink response in the anterior interpositus nucleus. Behavioral Neuroscience, 116, 22–36.
Nolan, B. C., & Freeman, J. H., Jr. (2005). Purkinje cell loss by OX7-saporin impairs excitatory and inhibitory eyeblink conditioning. Behavioral Neuroscience, 119, 190–201.
Nolan, B. C., & Freeman, J. H., [Jr.] (2006). Purkinje cell loss by OX7-saporin impairs acquisition and extinction of eyeblink conditioning. Learning & Memory, 13, 359–365.
Pavlov, I. P. (1927). Conditioned reflexes: An investigation of the physiological activity of the cerebral cortex (G. V. Anrep., Trans. & Ed.). London: Oxford University Press.
Rescorla, R. A. (1969). Pavlovian conditioned inhibition. Psychological Bulletin, 72, 77–94.
Rescorla, R. A. (1982). Some consequences of associations between the excitor and the inhibitor in a conditioned inhibition paradigm. Journal of Experimental Psychology: Animal Behavior Processes, 8, 288–298.
Rescorla, R. A., & LoLordo, V. M. (1965). Inhibition of avoidance behavior. Journal of Comparative & Physiological Psychology, 59, 406–412.
Schreurs, B. G., & Kehoe, E. J. (1987). Cross-modal transfer as a function of initial training level in classical conditioning with the rabbit. Learning & Behavior, 15, 47–54.
Urcelay, G. P., & Miller, R. R. (2006). A comparator view of Pavlovian and differential inhibition. Journal of Experimental Psychology: Animal Behavior Processes, 32, 271–283.
Wagner, A. R., & Rescorla, R. A. (1972). Inhibition in Pavlovian conditioning: Applications of a theory. In R. A. Boakes & M. S. Halliday (Eds.), Inhibition and learning (pp. 301–366). London: Academic Press.
Weidemann, G., & Kehoe, E. J. (2005). Stimulus specificity of concurrent recovery in the rabbit nictitating membrane response. Learning & Behavior, 33, 343–362.
Williams, D. A., Travis, G. M., & Overmier, J. B. (1986). Withincompound associations modulate the relative effectiveness of differential and Pavlovian conditioned inhibition procedures. Journal of Experimental Psychology: Animal Behavior Processes, 12, 351–362.
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This research was supported by National Institute for Mental Health Grant MH065483.
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Campolattaro, M.M., Schnitker, K.M. & Freeman, J.H. Changes in inhibition during differential eyeblink conditioning with increased training. Learning & Behavior 36, 159–165 (2008). https://doi.org/10.3758/LB.36.2.159
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DOI: https://doi.org/10.3758/LB.36.2.159