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Cognitive, Affective, & Behavioral Neuroscience

, Volume 7, Issue 4, pp 317–326 | Cite as

Avoiding another mistake: Error and posterror neural activity associated with adaptive posterror behavior change

  • Robert HesterEmail author
  • Natalie Barre
  • Jason B. Mattingley
  • John J. Foxe
  • Hugh Garavan
Article

Abstract

The magnitude of posterior medial frontal cortex (pMFC) activity during commission of an error has been shown to relate to adaptive posterror changes in response behavior on the trial immediately following. In the present article, we examined neural activity during and after error commission to identify its relationship to sustained posterror behavior changes that led to performance improvements several trials into the future. The standard task required participants to inhibit a prepotent motor response during infrequent lure trials, which were randomly interspersed among numerous go trials. Posterror behavior was manipulated by introducing a dynamic condition, in which an error on a lure trial ensured that the next lure would appear within two to seven go trials. Behavioral data indicated significantly higher levels of posterror slowing and accuracy during the dynamic condition, as well as fewer consecutive lure errors. Bilateral prefrontal cortex (PFC) and pMFC activity during the posterror period, but not during commission of the error itself, was associated with increased posterror slowing. Activity within two of these regions (right PFC and pMFC) also predicted success on the next lure trial. The findings support a relationship between pMFC/PFC activity and adaptive posterror behavior change, and the discrepancy between these findings and those of previous studies—in the present study, this relationship was detected during the posterror period rather than during commission of the error itself—may have resulted from the requirements of the present task. Implications of this discrepancy for the flexibility of cognitive control are discussed.

Keywords

Anterior Cingulate Cortex Dynamic Condition Cognitive Control Default Mode Network Blood Oxygen Level Dependent 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Psychonomic Society, Inc. 2007

Authors and Affiliations

  • Robert Hester
    • 1
    Email author
  • Natalie Barre
    • 2
  • Jason B. Mattingley
    • 1
  • John J. Foxe
    • 3
  • Hugh Garavan
    • 3
    • 4
  1. 1.Queensland Brain InstituteUniversity of QueenslandSt. LuciaAustralia
  2. 2.University of MelbourneParkvilleAustralia
  3. 3.Nathan S. Kline Institute for Psychiatric ResearchOrangeburg
  4. 4.Trinity CollegeDublinIreland

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