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Individual differences in trait rumination and the neural systems supporting cognitive reappraisal

  • Rebecca D. Ray
  • Kevin N. Ochsner
  • Jeffrey C. Cooper
  • Elaine R. Robertson
  • John D. E. Gabrieli
  • James J. Gross
Article

Abstract

Cognitive reappraisal can alter emotional responses by changing one’s interpretation of a situation’s meaning. Functional neuroimaging has revealed that using cognitive reappraisal to increase or decrease affective responses involves left prefrontal activation and goal-appropriate increases or decreases in amygdala activation (Ochsner, Bunge, Gross, & Gabrieli, 2002; Ochsner, Ray, et al., 2004). The present study was designed to examine whether patterns of brain activation during reappraisal vary in relation to individual differences in trait rumination, which is the tendency to focus on negative aspects of one’s self or negative interpretations of one’s life. Individual differences in rumination correlated with increases in amygdala response when participants were increasing negative affect and with greater decreases in prefrontal regions implicated in self-focused thought when participants were decreasing negative affect. Thus, the propensity to ruminate may reflect altered recruitment of mechanisms that potentiate negative affect. These findings clarify relations between rumination and emotion regulation processes and may have important implications for mood and anxiety disorders.

Keywords

Negative Affect Emotion Regulation Cognitive Reappraisal Neutral Picture Neutral Image 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Anderson, A. K., Christoff, K., Panitz, D., De Rosa, E., & Gabrieli, J. D. E. (2003). Neural correlates of the automatic processing of threat facial signals. Journal of Neuroscience, 23, 5627–5633.PubMedGoogle Scholar
  2. Anderson, A. K., & Phelps, E. A. (2001). Lesions of the human amygdala impair enhanced perception of emotionally salient events. Nature, 411, 305–309.CrossRefPubMedGoogle Scholar
  3. Beauregard, M., Lévesque, J., & Bourgouin, P. (2001). Neural correlates of conscious self-regulation of emotion. Journal of Neuroscience, 21, 6993–7000.Google Scholar
  4. Bechara, A., Damasio, H., & Damasio, A. R. (2000). Emotion, decision making and the orbital frontal cortex. Cerebral Cortex, 10, 295–307.CrossRefPubMedGoogle Scholar
  5. Bushman, B. J. (2002). Does venting anger feed or extinguish the flame? Catharsis, rumination, distraction, anger, and aggressive responding. Personality & Social Psychology Bulletin, 28, 724–731.CrossRefGoogle Scholar
  6. Cahill, L., Haier, R. J., White, N. S., Fallon, J., Kilpatrick, L., Lawrence, C., Potkin, S. G., & Alkire, M. T. (2001). Sex-related difference in amygdala activity during emotionally influenced memory storage. Neurobiology of Learning & Memory, 75, 1–9.CrossRefGoogle Scholar
  7. Canli, T., Desmond, J. E., Zhao, Z., & Gabrieli, J. D. E. (2002). Sex differences in the neural basis of emotional memories. Proceedings of the National Academy of Sciences, 99, 10789–10794.CrossRefGoogle Scholar
  8. Canli, T., Sivers, H., Whitfield, S. L., Gotlib, I. H., & Gabrieli, J. D. E. (2002). Amygdala response to happy faces as a function of extraversion. Science, 296, 2191.CrossRefPubMedGoogle Scholar
  9. Canli, T., Zhao, Z., Desmond, J. E., Kang, E., Gross, J. J., & Gabrieli, J. D. E. (2001). An f MRI study of personality influences on brain reactivity to emotional stimuli. Behavioral Neuroscience, 115, 33–42.CrossRefPubMedGoogle Scholar
  10. Christoff, K., Ream, J. M., Geddes, L. P. T., & Gabrieli, J. D. E. (2003). Evaluating self-generated information: Anterior prefrontal contributions to human cognition. Behavioral Neuroscience, 117, 1161–1168.CrossRefPubMedGoogle Scholar
  11. Cohen, J., MacWhinney, B., Flatt, M., & Provost, J. (1993). PsyScope: An interactive graphic system for designing and controlling experiments in the psychology laboratory using Macintosh computers. Behavior Research Methods, Instruments, & Computers, 25, 257–271.Google Scholar
  12. Craik, F. I. M., Moroz, T. M., Moscovitch, M., Stuss, D. T., Winocur, G., Tulving, E., & Kapur, S. (1999). In search of the self: A positron emission tomography study. Psychological Science, 10, 26–34.CrossRefGoogle Scholar
  13. Davis, R. N., & Nolen-Hoeksema, S. (2000). Cognitive inflexibility among ruminators and nonruminators. Cognitive Therapy & Research, 24, 699–711.CrossRefGoogle Scholar
  14. D’Esposito, M., Postle, B. R., & Rypma, B. (2000). Prefrontal cortical contributions to working memory: Evidence from event-related fMRI studies. Experimental Brain Research, 133, 3–11.CrossRefGoogle Scholar
  15. Fossati, P., Hevenor, S. J., Graham, S. J., Grady, C., Keightley, M. L., Craik, F. [I. M.], & Mayberg, H. (2003). In search of the emotional self: An f MRI study using positive and negative emotional words. American Journal of Psychiatry, 160, 1938–1945.CrossRefPubMedGoogle Scholar
  16. Frijda, N. H. (1986). The emotions. Cambridge: Cambridge University Press.Google Scholar
  17. Frith, C. D., & Frith, U. (1999). Interacting minds—A biological basis. Science, 286, 1692–1695.CrossRefPubMedGoogle Scholar
  18. Gallagher, H. L., & Frith, C. D. (2003). Functional imaging of “theory of mind”. Trends in Cognitive Sciences, 7, 77–83.CrossRefPubMedGoogle Scholar
  19. Glover, G. H. (1999). 3D z-shim method for reduction of susceptibility effects in BOLD fMRI. Magnetic Resonance in Medicine, 42, 290–299.CrossRefPubMedGoogle Scholar
  20. Glover, G. H., & Law, C. S. (2001). Spiral in/out BOLD fMRI for increased SNR and reduced susceptibility artifacts. Magnetic Resonance in Medicine, 46, 515–522.CrossRefPubMedGoogle Scholar
  21. Gross, J. J. (1998). The emerging field of emotion regulation: An integrative review. Review of General Psychology, 2, 271–299.CrossRefGoogle Scholar
  22. Gross, J. J. (2001). Emotion regulation in adulthood: Timing is everything. Current Directions in Psychological Science, 10, 214–219.CrossRefGoogle Scholar
  23. Gross, J. J. (2002). Emotion regulation: Affective, cognitive, and social consequences. Psychophysiology, 39, 281–291.CrossRefPubMedGoogle Scholar
  24. Gross, J. J., & John, O. P. (2003). Individual differences in two emotion regulation processes: Implications for affect, relationships, and well-being. Journal of Personality & Social Psychology, 85, 348–362.CrossRefGoogle Scholar
  25. Gusnard, D. A., & Raichle, M. E. (2001). Searching for a baseline: Functional imaging and the resting human brain. Nature Reviews Neuroscience, 2, 685–694.CrossRefPubMedGoogle Scholar
  26. Hamann, S. B., Monarch, E. S., & Goldstein, F. C. (2000). Memory enhancement for emotional stimuli is impaired in early Alzheimer’s disease. Neuropsychology, 14, 82–92.CrossRefPubMedGoogle Scholar
  27. Hariri, A. R., Mattay, V. S., Tessitore, A., Kolachana, B., Fera, F., Goldman, D., Egan, M. F., & Weinberger, D. R. (2002). Serotonin transporter genetic variation and the response of the human amygdala. Science, 297, 400–403.CrossRefPubMedGoogle Scholar
  28. Jackson, D. C., Malmstadt, J. R., Larson, C. L., & Davidson, R. J. (2000). Suppression and enhancement of emotional responses to unpleasant pictures. Psychophysiology, 37, 515–522.CrossRefPubMedGoogle Scholar
  29. Johnson, S. C., Baxter, L. C., Wilder, L. S., Pipe, J. G., Heiserman, J. E., & Prigatano, G. P. (2002). Neural correlates of self-reflection. Brain, 125, 1808–1814.CrossRefPubMedGoogle Scholar
  30. Kagan J. (1994). Galen’s prophecy: Temperament in human nature. New York: Basic BooksGoogle Scholar
  31. Keightley, M. L., Winocur, G., Graham, S. J., Mayberg, H. S., Hevenor, S. J., & Grady, C. J. (2003). An fMRI study investigating cognitive modulation of brain regions associated with emotional processing of visual stimuli. Neuropsychologia, 41, 585–596.CrossRefPubMedGoogle Scholar
  32. Kelley, W. M., Macrae, C. N., Wyland, C. L., Caglar, S., Inati, S., & Heatherton, T. F. (2002). Finding the self? An event-related fMRI study. Journal of Cognitive Neuroscience, 14, 785–794.CrossRefPubMedGoogle Scholar
  33. Kircher, T. T., Brammer, M., Bullmore, E., Simmons, A., Bartels, M., & David, A. S. (2002). The neural correlates of intentional and incidental self processing. Neuropsychologia, 40, 683–692.CrossRefPubMedGoogle Scholar
  34. Kjaer, T.W., Nowak, M., & Lou, H. C. (2002). Reflective self-awareness and conscious states: PET evidence for a common midline parietofrontal core. NeuroImage, 17, 1080–1086.CrossRefPubMedGoogle Scholar
  35. Kring, A. M., & Gordon, A. H. (1998). Sex differences in emotion: Expression, experience, and physiology. Journal of Personality & Social Psychology, 74, 686–703.CrossRefGoogle Scholar
  36. Lane, R. D., Fink, G. R., Chau, P. M., & Dolan, R. J. (1997). Neural activation during selective attention to selective emotional responses. NeuroReport, 8, 3969–3972.CrossRefPubMedGoogle Scholar
  37. Lane, R. D., Reiman, E. M., Axelrod, B., Yun, L.-S., Holmes, A., & Schwartz, G. E. (1998). Neural correlates of levels of emotional awareness: Evidence of an interaction between emotion and attention in the anterior cingulate cortex. Journal of Cognitive Neuroscience, 10, 525–535.CrossRefPubMedGoogle Scholar
  38. Lang, P. J., Greenwald, M. K., Bradley, M. M., & Hamm, A. O. (1993). Looking at pictures: Affective, facial, visceral, and behavioral reactions. Psychophysiology, 30, 261–273.CrossRefPubMedGoogle Scholar
  39. Lazarus, R. S. (1991). Emotion and adaptation. New York: Oxford University Press.Google Scholar
  40. LeDoux, J. E. (2000). Emotion circuits in the brain. Annual Review of Neuroscience, 23, 155–184.CrossRefPubMedGoogle Scholar
  41. Lévesque, J., Eugène, F., Joanette, Y., Paquette, V., Mensour, B., Beaudoin, G., Leroux, J.-M., Bourgouin, P., & Beauregard, M. (2003). Neural circuitry underlying voluntary suppression of sadness. Biological Psychiatry, 53, 502–510.CrossRefPubMedGoogle Scholar
  42. Lieberman, M. D., Jarcho, J. M., & Satpute, A. B. (2004). Evidencebased and intuition-based self-knowledge: An fMRI study. Journal of Personality & Social Psychology, 87, 421–435.CrossRefGoogle Scholar
  43. Macrae, C. N., Moran, J. M., Heatherton, T. F., Banfield, J. F., & Kelley, W. M. (2004). Medial prefrontal activity predicts memory for self. Cerebral Cortex, 14, 647–654.CrossRefPubMedGoogle Scholar
  44. Martin, L. L., & Tesser, A. (1996). Some ruminative thoughts. In R. S. Wyer, Jr. (Ed.), Advances in social cognition: IX. Ruminative thoughts (pp. 1–47). Mahwah, NJ: Erlbaum.Google Scholar
  45. McGuire, P. K., Paulesu, E., Frackowiak, R. S. J., & Frith, C. D. (1996). Brain activity during stimulus independent thought. Neuro-Report, 7, 2095–2099.Google Scholar
  46. Miller, E. K., & Cohen, J. D. (2001). An integrative theory of prefrontal cortical function. Annual Review of Neuroscience, 24, 167–202.CrossRefPubMedGoogle Scholar
  47. Morrow, J., & Nolen-Hoeksema, S. (1990). Effects of responses to depression on the remediation of depressive affect. Journal of Personality & Social Psychology, 58, 519–527.CrossRefGoogle Scholar
  48. Nolen-Hoeksema, S. (2000). The role of rumination in depressive disorders and mixed anxiety/depressive symptoms. Journal of Abnormal Psychology, 109, 504–511.CrossRefPubMedGoogle Scholar
  49. Nolen-Hoeksema, S., & Morrow, J. (1991). A prospective study of depression and posttraumatic stress symptoms after a natural disaster: The 1989 Loma Prieta earthquake. Journal of Personality & Social Psychology, 61, 115–121.CrossRefGoogle Scholar
  50. Nolen-Hoeksema, S., & Morrow, J. (1993). Effects of rumination and distraction on naturally occurring depressed mood. Cognition & Emotion, 7, 561–570.CrossRefGoogle Scholar
  51. Nolen-Hoeksema, S., Morrow, J., & Fredrickson, B. L. (1993). Response styles and the duration of episodes of depressed mood. Journal of Abnormal Psychology, 102, 20–28.CrossRefPubMedGoogle Scholar
  52. Ochsner, K. N. (in press). Characterizing the functional architecture of affect regulation: Emerging answers and outstanding questions. In J. T. Cacioppo, P. S.Visser, & C. L. Pickett (Eds.), Social neuroscience: People thinking about thinking people. Cambridge, MA: MIT Press.Google Scholar
  53. Ochsner, K. N., Bunge, S. A., Gross, J. J., & Gabrieli, J. D. E. (2002). Rethinking feelings: An fMRI study of the cognitive regulation of emotion. Journal of Cognitive Neuroscience, 14, 1215–1229.CrossRefPubMedGoogle Scholar
  54. Ochsner, K. N., & Gross, J. J. (2004). Thinking makes it so: A socialcognitive neuroscience approach to emotion regulation. In R. F. Baumeister & K. D. Vohs (Eds.), Handbook of self-regulation: Research, theory, and applications (pp. 229–255). New York: Guilford.Google Scholar
  55. Ochsner, K. N., & Gross, J. J. (2005). The cognitive control of emotion. Trends in Cognitive Sciences, 9, 242–249.CrossRefPubMedGoogle Scholar
  56. Ochsner, K. N., Knierim, K., Ludlow, D. H., Hanelin, J., Ramachandran, T., Glover, G., & Mackey, S. (2004). Reflecting upon feelings: An fMRI study of neural systems supporting the attributions of emotion to self and other. Journal of Cognitive Neuroscience, 16, 1748–1772.CrossRefGoogle Scholar
  57. Ochsner, K. N., Ray, R. D., Cooper, J. C., Robertson, E. R., Chopra, S., Gabrieli, J. D. E., & Gross, J. J. (2004). For better or for worse: Neural systems supporting the cognitive down- and up-regulation of negative emotion. NeuroImage, 23, 483–499.CrossRefPubMedGoogle Scholar
  58. Ochsner, K. N., Ray, R. D., Cooper, J. C., Robertson, E. R., Gabrieli, J. D. E., & Gross, J. J. (2005). Two routes to unhappiness: An fMRI study of the top-down and bottom-up generation of negative emotion. Manuscript in preparation.Google Scholar
  59. O’Doherty, J. P., Dayan, P., Friston, K., Critchley, H., & Dolan, R. J. (2003). Temporal difference models and reward-related learning in the human brain. Neuron, 28, 329–337.CrossRefGoogle Scholar
  60. O’Doherty, J. P., Kringelbach, M. L., Rolls, E. T., Hornak, J., & Andrews, C. (2001). Abstract reward and punishment representations in the human orbitofrontal cortex. Nature Neuroscience, 4, 95–102.CrossRefPubMedGoogle Scholar
  61. Papageorgiou, C., & Wells, A. (2003). An empirical test of a clinical metacognitive model of rumination and depression. Cognitive Therapy & Research, 27, 261–273.CrossRefGoogle Scholar
  62. Phan, K. L., Taylor, S. F., Welsh, R. C., Decker, L. R., Noll, D. C., Nichols, T. E., Britton, J. C., & Liberzon, I. (2003). Activation of medial prefrontal cortex and extended amygdala by individual ratings of emotional arousal: An fMRI study. Biological Psychiatry, 53, 211–215.CrossRefPubMedGoogle Scholar
  63. Preston, A. R., Thomason, M. E., Cooper, J. C., Ochsner, K. N., & Glover, G. H. (2004). Comparison of spiral-in/out and spiral-out BOLD fMRI at 1.5T and 3T. NeuroImage, 21, 291–301.CrossRefPubMedGoogle Scholar
  64. Ray, R. D., Ochsner, K. N., & Gross, J. J. (2005). Cognitive reappraisal modulates self-reported affect and physiology. Manuscript in preparation.Google Scholar
  65. Ray, R. D., Wilhelm, F. H., & Gross, J. J. (2005). All in the mind’s eye? Anger rumination and reappraisal. Manuscript submitted for publication.Google Scholar
  66. Richards, J. M., & Gross, J. J. (2000). Emotion regulation and memory: The cognitive costs of keeping one’s cool. Journal of Personality & Social Psychology, 79, 410–424.CrossRefGoogle Scholar
  67. Rolls, E. T. (2000). The orbitofrontal cortex and reward. Cerebral Cortex, 10, 284–294.CrossRefPubMedGoogle Scholar
  68. Rusting, C. L., & Nolen-Hoeksema, S. (1998). Regulating responses to anger: Effects of rumination and distraction on angry mood. Journal of Personality & Social Psychology, 74, 790–803.CrossRefGoogle Scholar
  69. Schaefer, S. M., Jackson, D. C., Davidson, R. J., Aguirre, G. K., Kimberg, D. Y., & Thompson-Schill, S. L. (2002). Modulation of amygdalar activity by the conscious regulation of negative emotion. Journal of Cognitive Neuroscience, 14, 913–921.CrossRefPubMedGoogle Scholar
  70. Segerstrom, S. C., Tsao, J. C. I., Alden, L. E., & Craske, M. G. (2000). Worry and rumination: Repetitive thought as a concomitant and predictor of negative mood. Cognitive Therapy & Research, 24, 671–688.CrossRefGoogle Scholar
  71. Siegle, G. J., Steinhauer, S. R., Thase, M. E., Stenger, V. A., & Carter, C. S. (2002). Can’t shake that feeling: Event-related fMRI assessment of sustained amygdala activity in response to emotional information in depressed individuals. Biological Psychiatry, 51, 693–707.CrossRefPubMedGoogle Scholar
  72. Simpson, C., & Papageorgiou, C. (2003). Metacognitive beliefs about rumination in anger. Cognitive & Behavioral Practice, 10, 91–94.CrossRefGoogle Scholar
  73. Smith, E. E., & Jonides, J. (1999). Storage and executive processes in the frontal lobes. Science, 283, 1657–1661.CrossRefPubMedGoogle Scholar
  74. Spasojevic, J., & Alloy, L. B. (2001). Rumination as a common mechanism relating depressive risk factors to depression. Emotion, 1, 25–37.CrossRefPubMedGoogle Scholar
  75. Steele, J. D., & Lawrie, S. M. (2004). Segregation of cognitive and emotional function in the prefrontal cortex: A stereotactic meta-analysis. NeuroImage, 21, 868–875.CrossRefPubMedGoogle Scholar
  76. Sukhodolsky, D. G., Golub, A., & Cromwell, E. N. (2001). Development and validation of the anger rumination scale. Personality & Individual Differences, 31, 689–700.CrossRefGoogle Scholar
  77. Trapnell, P. D., & Campbell, J. D. (1999). Private self-consciousness and the five-factor model of personality: Distinguishing rumination from reflection. Journal of Personality & Social Psychology, 76, 284–304.CrossRefGoogle Scholar
  78. Trask, P. C., & Sigmon, S. T. (1999). Ruminating and distracting: The effects of sequential tasks on depressed mood. Cognitive Therapy & Research, 23, 231–246.CrossRefGoogle Scholar
  79. Treynor, W., Gonzales, R., & Nolen-Hoeksema, S. (2003). Rumination reconsidered: A psychometric analysis. Cognitive Therapy & Research, 27, 247–259.CrossRefGoogle Scholar
  80. Vickers, K. S., & Vogeltanz-Holm, N. D. (2003). The effects of rumination and distraction tasks on psychophysiological responses and mood in dysphoric and nondysphoric individuals. Cognitive Therapy & Research, 27, 331–348.CrossRefGoogle Scholar
  81. Ward, A., Lyubomirsky, S., Sousa, L., & Nolen-Hoeksema, S. (2003). Can’t quite commit: Rumination and uncertainty. Personality & Social Psychology Bulletin, 29, 96–107.CrossRefGoogle Scholar
  82. Watkins, E., & Brown, R. G. (2002). Rumination and executive function in depression: An experimental study. Journal of Neurology, Neurosurgery, & Psychiatry, 72, 400–402.CrossRefGoogle Scholar
  83. Whalen, P. J., Rauch, S. L., Etcoff, N. L., McInerney, S. C., Lee, M. B., & Jenike, M. A. (1998). Masked presentation of emotional facial expressions modulate amygdala activity without explicit knowledge. Journal of Neuroscience, 18, 411–418.PubMedGoogle Scholar

Copyright information

© Psychonomic Society, Inc. 2005

Authors and Affiliations

  • Rebecca D. Ray
    • 1
  • Kevin N. Ochsner
    • 2
  • Jeffrey C. Cooper
    • 1
  • Elaine R. Robertson
    • 1
  • John D. E. Gabrieli
    • 1
  • James J. Gross
    • 1
  1. 1.Department of PsychologyStanford UniversityStanford
  2. 2.Columbia UniversityNew York

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