Abstract
The purpose of the study was to determine whether the escape response in a survival situation might not be modified in some way by moderate dosages of CPZ. The procedure used provided two measures, swimming time and success or failure in escaping from a submerged linear runway whose exit was blocked by an oncoming opponent. Three drug levels were selected: 1.0, 2.5, and 4.0 mg/kg CPZ. Measured on the variable of success in the escape situation, the escape response was altered by the administration of CPZ. Measured on the variable of swimming time, the escape response was not altered by the administration of CPZ.
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COOK, L., & WEIDLEY, E. Behavioral effects of some psycho-pharmacological agents. Annals of the New York Academy of Sciences, 1957, 66, 740–752.
COURVOISIER, S., FOURNEL, J., DUCROT, R., KOLSKY, M., & KOETSCHET, P. Propriétés pharmacodynamiques du chlorhydrate de chloro-3 (diméthylamino-3 propyl)-10 phénothiazine (4.560 R.P.). Archives International Pharmacodynamie, 1953, 92, 305–361. Cited by P. B. Dews and W. H. Morse, Annual Re view of Pharmacology, 1961, 1, 149.
DEWS, P. B., & MORSE, W. H. Behavioral pharmacology. Annual Review of Pharmacology, 1961, 1, 145–74.
DOMINO, E. F., KAROLY, A. J., & WALKER, E. L. Effects of various drugs on a conditioned avoidance response in dogs resistant to extinction. Journal of Pharmacology & Experimental Therapeutics, 1963, 141, 92–99.
GOLLUB, L. R., & BRADY, J. V. Behavioral pharmacology. Annual Review of Pharmacology, 1965, 5, 235–62.
HEISE, G. A., & BOFF, E. Continuous avoidance as a base-line for measuring behavioral effects of drugs. Psychopharmacologia, 1962, 3, 264–82.
HUGHES, F. W., & KOPMANN, E. Influence of pentobarbital, hydroxyzine, chlorpromazine, reserpine, and meprobamate on choice-discrimination behavior in the rat. Archives International Pharmacodynamie, 1960, 126, 158–70.
SCHUMSKY, D. A., & JONES, P. D. Reliable paired comparison dominance orders in rats. The Psychological Record, 1966, 16, 473–78.
SIEGEL, S. Nonparametric statistics for the behavioral sciences. New York: McGraw-Hill, 1956.
UYENO, E. T., & WHITE, M. Social isolation and dominance behavior. Journal of Comparative & Physiological Psychology, 1967, 63, 157–59.
VERHAVE, T., OWEN, J. E., & SLATER, O. H. Effects of various drugs on escape and avoidance behavior. In H. H. Pennes (Ed.), Progress in neurobiology. III. Psychopharmacology. New York: Harper Brothers, 1958. Pp. 267–279.
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Lloyd, M., Harrigan, J.E. The effect of chlorpromazine on survival motivated escape response. Psychon Sci 13, 147–148 (1968). https://doi.org/10.3758/BF03342453
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DOI: https://doi.org/10.3758/BF03342453