Abstract
Rats injected with magnesium pemoline reached acquisition criterion in a visual discrimination task with significantly fewer reinforced trials than control Ss. However, on retention tests given four and six weeks later, control Ss performed significantly better than drug Ss. The results suggest that magnesium pemoline enhances stimulus responsiveness and motor activity rather than directly affecting central learning processes.
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We thank Dr. H. G. Schoepke, Abbott Laboratories, for providing the magnesium pemoline. This investigation was partially supported by Public Health Service Training Grant No. NB05411 from the Institute of Neurological Diseases and Blindness.
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Scholz, K.W., Peeler, D.F. & Ward, O.B. Magnesium pemoline: Effect on food reinforced discrimination performance in rats. Psychon Sci 13, 145–146 (1968). https://doi.org/10.3758/BF03342452
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DOI: https://doi.org/10.3758/BF03342452