Abstract
Magnesium pemoline was found to have a differential effect on behavior depending upon genotype. The drug resulted in increased activity and reduced avoidance scores for the fast-conditioning C3H strain of mice, whereas it significantly increased avoidance scores and activity for the slow-conditioning ST/bJ strain. The effect of magnesium pemoline on behavior is discussed in terms of an inverted-U relationship between reactivity and learning.
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Yeudall, L.T., Poley, W. & Royce, J.R. Effect of magnesium pemoline on avoidance conditioning and intertrial activity in two strains of inbred mice. Psychon. Sci. 17, 299–301 (1969). https://doi.org/10.3758/BF03336541
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DOI: https://doi.org/10.3758/BF03336541