Abstract
Rats with hippocampal lesions (n = 16), sham-operated controls (n = 5), and unoperated controls (n = 8) were trained on place and cue tasks in an elevated radial arm maze. Hippocampallesioned rats had impaired working memory and impaired cognitive-map formation. The behavior of the hippocampals in choosing arms was different from that of the controls even immediately after training began. The hippocampals were not able to rapidly perceive the spatial requirements of the task and did not show the inherent stereotyped behavior employed by controls. Nonetheless, the hippocampals showed that they could learn problem-solving behavior as training progresses.
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Beatty, W. W., & Shavalia, D. A. (1980). Spatial memory in rats: Time course of working memory and effect of anesthetics. Behavioral & Neural Biology, 28, 454–462.
Bolhouis, J. J., Bijlsma, S., & Ansmink, P. (1986). Exponential decay of spatial memory of rats in a radial maze. Behavioral & Neural Biology, 46, 115–122.
Crusio, W. E., Schwegler, H., & Lipp, H. P. (1987). Radial-maze performance and structural variation of the hippocampus in mice: A correlation with mossy fiber distribution. Brain Research, 425, 182–185.
Dale, R. H. I., & Innis, N. K. (1986). Interactions between response stereotypy and memory strategies on the eight-arm radial maze. Behavioral Brain Research, 19, 17–25.
Foreman, N. (1985). Algorithmic responding on the radial maze in rats does not always imply absence of spatial encoding. Quarterly Journal of Experimental Psychology, 37, 333–358.
Jarrard, L. E. (1983). Selective hippocampal lesions and behavior: Effects of kainic acid lesions on performance of place and cue tasks. Behavioral Neuroscience, 97, 873–889.
Jarrard, L. E., Okaichi, H., Steward, O., & Goldschmidt, R. B. (1984). On the role of the performance of place and cue tasks: Comparisons with damage to hippocampus. Behavioral Neuroscience, 98, 946–954.
Maki, W. S., Brokofsky, S., & Berg, B. (1979). Spatial memory in rats: Resistance to retroactive interference. Animal Learning & Behavior, 7, 25–30.
Morris, R. G. M., Garrud, P., Rawlins, J. N. P., & O’Keefe, J. (1982). Place navigation impaired in rats with hippocampal lesions. Nature, 297, 681–683.
Nadel, L., & MacDonald, L. (1980). Hippocampus: Cognitive map or working memory? Behavioral & Neural Biology, 29, 405–409.
Okaichi, H. (1987). Performance and dominant strategies on place and cue tasks following hippocampal lesions in rats. Psychobiology, 15, 58–63.
O’Keefe, J., & Nadel, L. (1978). The hippocampus as a cognitive map. Oxford: Clarendon Press.
Olton, D. S. (1979). Maze, maps, and memory. American Psychologist, 34, 583–596.
Olton, D. S., Becker, J. T., & Handelmann, G. E. (1979). Hippocampus, space, and memory. Behavioral & Brain Science, 2, 313–365.
Olton, D. S., Collison, C., & Werz, M. A. (1977). Spatial memory and radial arm maze performance of rats. Learning & Motivation, 8, 289–314.
Olton, D. S., & Feustle, W. A. (1981). Hippocampal function required for nonspatial working memory. Experimental Brain Research, 41, 380–389.
Olton, D. S., & Papas, B. C. (1979). Spatial memory and hippocampal function. Neuropsychologia, 17, 669–682.
Olton, D. S., & Samuelson, R. J. (1976). Remembrance of places passed: Spatial memory in rats. Journal of Experimental Psychology: Animal Behavior Processes, 2, 97–116.
Olton, D. S., & Werz, M. A. (1978). Hippocampal function and behavior: Spatial discrimination and response inhibition. Physiology & Behavior, 20, 597–605.
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Okaichi, H., Oshima, Y. Choice behavior of hippocampectomized rats in the radial arm maze. Psychobiology 18, 416–421 (1990). https://doi.org/10.3758/BF03333088
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DOI: https://doi.org/10.3758/BF03333088