Abstract
Rats with hippocampal ablations, those with cortical control lesions, and normals were trained on a go/no-go single-alternation task in an operant situation. Hippocampectomized animals were facilitated, compared to normals, in acquisition in terms of latency measure (latency to first press on go trials/latency to first press on no-go trials). Cortically ablated animals were deficient compared to normals, in terms of a response measure (total responses on no-go trials/total responses on go trials). An SD was added to go trials after the animals attained a low-level criterion and was eliminated after 10 sessions. As measured by performance tests given after elimination of the SD, no group differences were found in utilization of the SD.
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Supported by Grants MH-12574, MH-10320, MS-16384-01, and the Veterans Administration.
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Walker, D.W., Means, L.W. & Isaacson, R.L. The effects of hippocampal and cortical lesions on single-alternation go, no-go acquisition in rats. Psychon Sci 21, 29–31 (1970). https://doi.org/10.3758/BF03332419
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DOI: https://doi.org/10.3758/BF03332419