Abstract
Four groups of rats were trained on a two lever spatial discrimination problem. Ss injected with pentobarbital during acquisition and placebo during reversal learned the discrimination reversal with fewer errors than control group Ss which never received pentobarbital. Administering pentobarbital only during reversal learning impaired acquisition of the new response.
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1. In conducting the research reported herein, the investigators adhered to the “Principles of laboratory animal care” as established by the National Society for Medical Research.
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Meltzer, D., Merkler, N.L. & Maxey, G.C. Discrimination reversal under sodium pentobarbital. Psychon Sci 5, 413–414 (1966). https://doi.org/10.3758/BF03331024
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DOI: https://doi.org/10.3758/BF03331024