Abstract
An attempt was made to transfer a learned response between individual rats by means of brain extracts containing RNA. Donors were trained on a light-dark discrimination task with a food reward in a “Y” maze. Control groups consisted of donors given non-discriminative experience in the maze equal to that of the trained group, donors maintained in their home cages, and a saline control group. Recipient Ss did not differ significantly either in the number of errors made during training, or in the number of trials necessary to meet a criterion of five consecutive correct responses.
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ALBERT, D. J. Memory in mammals: Evidence for a system involving nuclear RNA. Neuropsychologia, 1966, 47, 79–91.
BABICH, F. R., JACOBSON, A. L., BUBASH, S., & JACOBSON, A. Transfer of a response to naive rats by injection of RNA extracted from trained rats. Science, 1965, 149, 656–657.
GROSS, C. G., & CAREY, F. M. Transfer of learned response by RNA injection: Failure of attempts to replicate. Science, 1965, 150, 1749.
HYDEN, H., & EGYHAZI, E. Nuclear RNA changes of nerve cells during a learning experiment in rats. Proc. Nat. Acad. Sci., 1962, 48, 1366.
JACOBSON, A. L., BABICH, F. R., BUBASH, S., & JACOBSON, A. Differential approach tendencies produced by injection of RNA from trained rats. Science, 1965, 150, 636–637.
KIMBLE, R. J., & KIMBLE, D. P. Failure to find “transfer of training” effects via RNA from trained rats injected into naive rats. Worm Runners’ Digest, 1966, 8, 32–36.
LUTTGES, M., JOHNSON, T., BUCK, C., HOLLAND, J., & McGAUGH, J. An examination of transfer of learning by nucleic acid. Science, 1966, 151, 834–837.
SVED, S. The metabolism of exogenous RNA injected into mice. Canad. J. Biochem., 1965, 43, 946–958.
UNGAR, C., & OCEGUERA-NAVARRO, G. Transfer of habitation by material extracted from brain. Nature, 1965, 207, 301–302.
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1. This research was supported in part by National Science Foundation Undergraduate Research Participation Grant GY-136.
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Hoffmann, R.F., Stewart, C.N. & Bhagavan, H.N. Failure to transfer a learned response in rats using a brain extract containing RNA. Psychon Sci 9, 151–152 (1967). https://doi.org/10.3758/BF03330804
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DOI: https://doi.org/10.3758/BF03330804