Abstract
Sprague-Dawley albino rats were given maze exploration and escape training in a straight-runway maze. Ss in Control Group 1 were given only maze exploration, and those in Control Group 2 had no maze experiences. Half the Ss from each of the groups were sacrificed immediately, and the remainder were sacrificed 2 h after completing training. The brains were analyzed for protein, RNA, and total nitrogen. A significant increase in brain protein was found for the 2-h sacrifice escape condition. Moreover, estimates of NPN (nonprotein nitrogen) were significantly lower in this experimental condition.
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Gold, M., Altschuler, H., Kleban, M.H. et al. Chemical changes in the rat brain following escape training. Psychon Sci 17, 37–38 (1969). https://doi.org/10.3758/BF03329156
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DOI: https://doi.org/10.3758/BF03329156