Abstract
The drinking response to hypertonic loads can be depressed by frontal pole and/or olfactory bulb lesions. In order to evaluate the role of each of these structures, 36 rats were mechanically or electrolytically lesioned in the olfactory bulbs or frontal poles. Following hypertonic loading by IP injection of NaCl, animals with olfactory lesions always drank like normal control animals, while animals with frontal lesions showed depressed, normal, or elevated drinking responses. These results were interpreted in relation to the known physiology of the hypothalamus and connections between hypothalamus and frontal poles.
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Wilcove, W.G., Vance, W.B. The effects of olfactory and frontal pole lesions on the drinking response to hypertonic loading in rats. Psychon Sci 27, 295–298 (1972). https://doi.org/10.3758/BF03328969
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DOI: https://doi.org/10.3758/BF03328969