Abstract
Rats with unilateral, one-stage bilateral, and two-stage bilateral lesions, at 10-day intervals, of the lateral septal area were tested for acquisition of two-way active avoidance behavior in the shuttlebox. Performance was enhanced with one-stage bilateral lesions, but no significant enhancement was observed with unilateral or two-stage bilateral lesions. These results indicate that recovery of this aspect of septal function occurs when bilateral lesions are spaced by 10 days.
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Finger, S., Walbran, B., & Stein, D. G. Brain damage and behavioral recovery: Serial lesion phenomena. Brain Research, 1973, in press.
Hamilton, L., Kelsey, J., Grossman, S. Variations in behavioral inhibitions following different septal lesions in rats. Journal of Comparative & Physiological Psychology, 1970, 70, 79–86.
Johnson, D. A. Developmental aspects of recovery of function following septal lesions in the infant rat. Journal of Comparative & Physiological Psychology, 1972, 78, 331–348.
Kenyon, J., & Krieckhaus, E. Enhanced avoidance behavior following septal lesions in the rat as a function of lesion size and spontaneous activity. Journal of Comparative & Physiological Psychology, 1965, 59, 466–469.
Kramer, C. Y. Extension of multiple range tests to group means with unequal numbers of replications. Biometrices, 1956, 12, 307–310.
Krieckhaus, E., Simmons, H., Thomas, G., & Kenyon, J. Septal lesions enhance shock avoidance behavior in the rat. Experimental Neurology, 1964, 9, 106–113.
LeVere, T. E. Recovery of function after brainstem lesion in the rat. Journal of Comparative & Physiological Psychology, 1969, 69, 339–344.
Petrinovich, L., & Bliss, C. Retention of a learned brightness discrimination following ablations of the occipital cortex in the rat. Journal of Comparative & Physiological Psychology, 1966, 61, 136–138.
Raisman, G. Neuronal plasticity in the septal nuclei of the adult rat. Brain Research, 1969, 14, 25–48.
Schwartzbaum, J., Green, R., Beatty, W., & Thompson, J. Acquisition of avoidance behavior following septal lesions in the rat. Journal of Comparative & Physiological Psychology, 1967, 63, 95–104.
Skinner, J. E, Neuroscience: A laboratory manual. Philadelphia: Saunders, 1971.
Stein, D. G., Rosen, J. J., Graziadei, J., Mishkin, D., & Brink, J. J. Central nervous system: Recovery of function. Scinece, 1969, 166, 528–530.
Winer, B. J. Statistical principles in experimental design. New York: McGraw-Hill, 1962.
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This paper is sponsored by Steven F. Maier, who takes full editorial responsibility for its content. The authors thank William Greenough for his assistance.
Supported by USPHS No. 5, TO1 MH 10715-07.
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Kouba, F.C., Bussey, M.E. Two-way shuttle avoidance after simultaneous and staged lateral septal lesions in the rat. Bull. Psychon. Soc. 2, 111–112 (1973). https://doi.org/10.3758/BF03327735
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DOI: https://doi.org/10.3758/BF03327735