Abstract
Twenty-four differentially reared male rhesus monkeys were used as Ss in this experiment. For 30 days the animals were injected twice daily with trifluoperazine. The effects of these injections were measured on a match-to-sample task previously learned and on a number of blood biochemical assessments. Results indicated that (1) the drug reduced the sensitivity to shock in a shock-escape match-to-sample task according to degrees of previous environmental stimulation during early rearing; (2) the least affected Ss were the animals reared in strict isolation, animals reared in partial isolation and under normal social conditions were moderately affected, and animals reared in enriched environments were greatly affected; (3) these effects could be interpreted to indicate differential early threshold development in the four rearing groups used in this experiment; and (4) drug injections could be considered “therapeutic” in the same sense that social change was thought to be therapeutic in a previous study.
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1. This research was sponsored by AF Contract AF29600-67-C-0011 between Aeromedical Research Laboratory, Holloman AFB, New Mexico and Florida Presbyterian College.
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Angermeier, W.F., Phelps, J.B., Reynolds, H.H. et al. Early environment and behavioral-biochemical response to trifluoperazine in monkeys. Psychon Sci 11, 231–232 (1968). https://doi.org/10.3758/BF03327675
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DOI: https://doi.org/10.3758/BF03327675