Abstract
Puromycin appears to block long-term memory of color discrimination training (measured 3 days after initial training) and inhibits its acquisition (measured as the number of days taken to reach the task criterion). The antibiotic has no effect on long-term memory of pattern discrimination, although it does affect acquisition to criterion. These results suggest that puromycin’s influence on long-term memory is a function of the extent of long-term memory formation on the initial day of training as determined by task difficulty.
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Mayor, S.J. Puromycin’s effects on long-term memory and the acquisition of two successive visual discrimination tasks in Japanese quail. Psychobiology 1, 33–36 (1973). https://doi.org/10.3758/BF03326864
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DOI: https://doi.org/10.3758/BF03326864