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PET studies of encoding and retrieval: The HERA model

Psychonomic Bulletin & Review volume 3, pages 135–148 (1996)Cite this article

Abstract

We review positron emission tomography (PET) studies whose results converge on the hemispheric encoding/retrieval asymmetry (HERA) model of the involvement of prefrontal cortical regions in the processes of human memory. The model holds that the left prefrontal cortex is differentially more involved in retrieval of information from semantic memory, and in simultaneously encoding novel aspects of the retrieved information into episodic memory, than is the right prefrontal cortex. The right prefrontal cortex, on the other hand, is differentially more involved in episodic memory retrieval than is the left prefrontal cortex. This general pattern holds for different kinds of information (e.g., verbal materials, pictures, faces) and a variety of conditions of encoding and retrieval.

References

  • Andreasen, N. C.,Arndt, S.,Cizadlo, T.,O’Leary, D. S.,Watkins, G. L.,Boles Ponto, L. L., &Hichwa, R. D. (1995).Sample size and statistical power in [15O] H 2 O studies of human cognition. Manuscript submitted for publication.

  • Andreasen, N. C.,O’Leary, D. S.,Arndt, S.,Cizadlo, T.,Hurtig, R.,Rezai, K.,Watkins, G. L.,Boles Ponto, L. L., &Hichwa, R. D. (1995a).Neural substrates of face recognition. Manuscript submitted for publication.

  • Andreasen, N. C., O’Leary, D. S., Arndt, S., Cizadlo, T., Hurtig, R., Rezai, K., Watkins, G. L., Boles Ponto, L. L., &Hichwa, R. D. (1995b). Short-term and long-term verbal memory: A positron emission tomography study.Proceedings of the National Academy of Science,92, 5111–5115.

    Article  Google Scholar 

  • Arndt, S., Cizadlo, T., Andreasen, N. C., Zeien, G., Harris, G., O’Leary, D. S., Watkins, G. L., Boles Ponto, L. L., &Hichwa, R. D. (1995). A comparison of approaches to the statistical analysis of [15O]H2O PET cognitive activation studies.Journal of Psychiatry,7, 155–168.

    Google Scholar 

  • Bäckman, L.,Almkvist, O.,Andersson, J.,Nordberg, A.,Windblad, B.,Reineck, R., &Långström, B. (1995).Brain activation in young and older adults during implicit and explicit retrieval. Manuscript submitted for publication.

  • Baron, J. C., Petit-Taboué, M. C., Le Doze, F., Desgranges, B., Ravenel, N., &Marchal, G. (1994). Right frontal cortex hypometabolism in transient global amnesia: A PET study.Brain,117, 545–552.

    Article  PubMed  Google Scholar 

  • Benson, D. F. (1988). Classical syndromes of aphasia. In F. Foller & J. Grafman (Eds.),Handbook of neuropsychology (Vol. 1, pp. 267–280). Amsterdam: Elsevier.

    Google Scholar 

  • Bottini, G., Corcoran, R., Sterzi, R., Paulesu, E., Schenone, P., Scarpa, P., Frackowiak, R. S. J., &Frith, C. D. (1994). The role of the right hemisphere in the interpretation of figurative aspects of language: A positron emission tomography activation study.Brain,117, 1241–1253.

    Article  PubMed  Google Scholar 

  • Buckner, R. (1996). Beyond HERA: Contributions of specific prefrontal brain areas to long-term memory retrieval.Psychonomic Bulletin & Review,3, 149–158.

    Google Scholar 

  • Buckner, R. L., Petersen, S. E., Ojemann, J. G., Miezin, F. M., Squire, L. R., &Raichle, M. E. (1995). Functional anatomical studies of explicit and implicit memory retrieval tasks.Journal of Neuroscience,15, 12–29.

    PubMed  Google Scholar 

  • Buckner, R. L., Raichle, M. E., Miezin, F. M., &Petersen, S. E. (1995). PET studies of the recall of pictures and words from memory.Society for Neuroscience Abstracts,21, 1441.

    Google Scholar 

  • Buckner, R. L., &Tulving, E. (1995). Neuroimaging studies of memory: Theory and recent PET results. In F. Boller & J. Grafman (Eds.),Handbook of neuropsychology (Vol. 10, pp. 439–466). Amsterdam: Elsevier.

    Google Scholar 

  • Butters, N., &Stuss, D. T. (1989). Diencephalic amnesia. In F. Boller & J. Grafman (Eds.),Handbook of neuropsychology (Vol. 3, pp. 107–148). Amsterdam: Elsevier.

    Google Scholar 

  • Cabeza, R.,Kapur, S.,Craik, F. I. M.,McIntosh, A. R.,Houle, S., &Tulving, E. (in press). Functional neuroanatomy of recall and recognition: A PET study of episodic memory.Journal of Cognitive Neuroscience.

  • Cabeza, R.,Tulving, E.,Kapur, S.,McIntosh, A. R.,Jennings, J. M.,Nyberg, L.,Houle, S. ,Craik, F. I. M. (1995).Age-related decreases and increases in brain activity during encoding, recall, and recognition. Manuscript in preparation.

  • Craik, F. I. M., &Jennings, J. M. (1992). Human memory. In F. I. M. Craik & T. A. Salthouse (Eds.),Handbook of aging and cognition (pp. 51–110). Hillsdale, NJ: Erlbaum.

    Google Scholar 

  • Craik, F. I. M., &Lockhart, R. S. (1972). Levels of processing: A framework for memory research.Journal of Verbal Learning & Verbal Behavior,11, 671–684.

    Article  Google Scholar 

  • Craik, F. I. M., &Tulving, E. (1975). Depth of processing and the retention of words in episodic memory.Journal of Experimental Psychology: General,104, 268–294.

    Article  Google Scholar 

  • Demb, J. B., Desmond, J. E., Wagner, A. D., Vaidya, C. J., Glover, G. H., &Gabrieli, J. D. E. (1995). Semantic encoding and retrieval in the left inferior prefrontal cortex: A functional MRI study of task difficulty and process specificity.Journal of Neuroscience,15, 5870–5878.

    PubMed  Google Scholar 

  • Démonet, J.-F., Chollet, F., Ramsay, S., Cardebat, D., Nespoulous, J.-L., Wise, R., Rascol, A., &Frackowiak, R. S. J. (1992). The anatomy of phonological and semantic processing in normal subjects.Brain,115, 1753–1768.

    Article  PubMed  Google Scholar 

  • Démonet, J.-F., Wise, R., &Frackowiak, R. S. J. (1993). Language functions explored in normal subjects by positron emission tomography: A critical review.Human Brain Mapping,1, 30–47.

    Article  Google Scholar 

  • Fletcher, P. C., Frith, C. D., Grasby, P. M., Shallice, T., Frackowiak, R. S. J., &Dolan, R. J. (1995). Brain systems for encoding and retrieval of auditory-verbal memory: An in vivo study in humans.Brain,118, 401–416.

    Article  PubMed  Google Scholar 

  • Fox, P. T. (1991). Physiological ROI definition by image subtraction.Journal of Cerebral Blood Flow & Metabolism,11, A79-A82.

    Google Scholar 

  • Fox, P. T., Mintun, M. A., Reiman, E. M., &Raichle, M. E. (1988). Enhanced detection of focal brain responses using intersubject averaging and change-distributed analysis of subtracted PET images.Journal of Cerebral Blood Flow & Metabolism,8, 642–653.

    Google Scholar 

  • Frackowiak, R. S. J. (1994). Functional mapping of verbal memory and language.Trends in Neurosciences,17, 109–115.

    Article  PubMed  Google Scholar 

  • Frackowiak, R. S. J., &Friston, K. J. (1994). Functional neuroanatomy of the human brain: Positron emission tomography—a new neuroanatomical technique.Journal of Anatomy,184, 211–225.

    PubMed  Google Scholar 

  • Friston, K. J., Frith, C. D., Liddle, P. F., &Frackowiak, R. S. J. (1991). Comparing functional (PET) images: The assessment of significant change.Journal of Cerebral Blood Flow & Metabolism,11, 690–699.

    Google Scholar 

  • Friston, K. J., Frith, C. D., Liddle, P. F., &Frackowiak, R. S. J. (1993). Functional connectivity: The principal-component analysis of large (PET) data sets.Journal of Cerebral Blood Flow & Metabolism,13, 5–14.

    Google Scholar 

  • Friston, K. J., Holmes, A. P., Worsley, K. J., Poline, J.-P., Frith, C. D., &Frackowiak, R. S. J. (1995). Statistical parametric maps in functional imaging: A general linear approach.Human Brain Mapping,2, 189–210.

    Article  Google Scholar 

  • Frith, C. D., Friston, K. J., Liddle, P. F., &Frackowiak, R. S. J. (1991a). A PET study of word finding.Neuropsychologia,29, 1137–1148.

    Article  PubMed  Google Scholar 

  • Frith, C. D., Friston, K. J., Liddle, P. F., &Frackowiak, R. S. J. (1991b). Willed action and the prefrontal cortex in man: A study with PET.Proceedings of the Royal Society of London: Series B,244, 241–246.

    Article  Google Scholar 

  • Geschwind, N. (1972). Language and the brain.Scientific American,226, 76–83.

    Article  PubMed  Google Scholar 

  • Grady, C. L., McIntosh, A. R., Horwitz, B., Maisog, J. M., Ungerleider, L. G., Mentis, M. J., Pietrini, P., Schapiro, M. B., &Haxby, J. V. (1995, July 14). Age-related reductions in human recognition memory due to impaired encoding.Science,269, 218–221.

    Article  PubMed  Google Scholar 

  • Grasby, P. M., Frith, C. D., Friston, K. J., Bench, C., Frackowiak, R. S. J., &Dolan, R. J. (1993). Functional mapping of brain areas implicated in auditory-verbal memory function.Brain,116, 1–20.

    Article  PubMed  Google Scholar 

  • Grasby, P. M., Frith, C. D., Friston, K. J., Simpson, J., Fletcher, P. C., Frackowiak, R. S. J., &Dolan, R. J. (1994). A graded task approach to the functional mapping of brain areas implicated in auditory-verbal memory.Brain,117, 1271–1282.

    Article  PubMed  Google Scholar 

  • Haxby, J. V., Horwitz, B., Maisog, J. M., Ungerleider, L. G., Mishkin, M., Schapiro, M. B., Rapoport, S. I., &Grady, C. L. (1993). Frontal and temporal participation in long-term recognition memory for faces: A PET-rCBF activation study.Journal of Cerebral Blood Flow & Metabolism,13 (Suppl. 1), 499.

    Google Scholar 

  • Haxby, J. V., Ungerleider, L. G., Horwitz, B., Maisog, J. M., Rapoport, S. L., &Grady, C. L. (1996). Face encoding and recognition in the human brain.Proceedings of the National Academy of Science,93, 922–927.

    Article  Google Scholar 

  • Hyde, T. S., &Jenkins, J. J. (1969). Differential effects of incidental tasks on the organization of recall of a list of highly associated words.Journal of Experimental Psychology,83, 472–481.

    Article  Google Scholar 

  • Jenkins, I. H., Brooks, D. J., Nixon, P. D., Frackowiak, R. S. J., &Passingham, R. E. (1994). Motor sequence learning: A study with positron emission tomography.Journal of Neuroscience,14, 3775–3790.

    PubMed  Google Scholar 

  • Jones-Gottman, M., Zatorre, R. J., Evans, A. C., &Meyer, E. (1993). Functional activation of right hippocampus during an olfactory recognition memory.Society for Neuroscience Abstracts,19, 1002.

    Google Scholar 

  • Jonides, J., Smith, E. E., Koeppe, R. A., Awh, E., Minoshima, S., &Mintun, M. A. (1993). Spatial working memory in humans as revealed by PET.Nature,363, 623–625.

    Article  PubMed  Google Scholar 

  • Kapur, N., Friston, K. J., Young, A., Frith, C. D., &Frackowiak, R. S. J. (1995). Activation of human hippocampal formation during memory for faces: A PET study.Cortex,31, 99–108.

    PubMed  Google Scholar 

  • Kapur, S., Craik, F. I. M., Jones, C., Brown, G. M., Houle, S., &Tulving, E. (1995). Functional role of the prefrontal cortex in memory retrieval: A PET study.Neuroreport,6, 1880–1884.

    Article  PubMed  Google Scholar 

  • Kapur, S., Craik, F. I. M., Tulving, E., Wilson, A. A., Houle, S., &Brown, G. M. (1994). Neuroanatomical correlates of encoding in episodic memory: Levels of processing effect.Proceedings of the National Academy of Science,91, 2008–2011.

    Article  Google Scholar 

  • Kapur, S., Rose, R., Liddle, P. F., Zipursky, R. B., Brown, G. M., Stuss, D., Houle, S., &Tulving, E. (1994). The role of left prefrontal cortex in verbal processing: Semantic processing or willed action?Neuroreport,5, 2193–2196.

    Article  PubMed  Google Scholar 

  • Kapur, S.,Tulving, E.,Cabeza, R.,McIntosh, A. R.,Houle, S., &Craik, F. I. M., (1996).The neural correlates of intentional learning of verbal materials: A PET study in humans. Manuscript in preparation.

  • Kinsbourne, M., &George, J. (1974). The mechanism of the wordfrequency effect on recognition memory.Journal of Verbal Learning & Verbal Behavior,13, 63–69.

    Article  Google Scholar 

  • Knight, R. T. (1984). Decreased response to novel stimuli after prefrontal lesions in man.Electroencephalography & Clinical Neurophysiology,59, 9–20.

    Article  Google Scholar 

  • Knight, R. T. (in press). Distributed cortical network for visual stimulus detection.Journal of Cognitive Neuroscience.

  • Köhler, S., Kapur, S., Moscovitch, M., Winocur, G., &Houle, S. (1995). Dissociation of pathways for object and spatial vision in the intact human brain.Neuroreport,6, 1865–1868.

    Article  PubMed  Google Scholar 

  • Kosslyn, S. M., Nathaniel, M. A., Thompson, W. L., Chabris, C. F., Rauch, S. L., &Anderson, A. K. (1994). Identifying objects seen from different viewpoints: A PET investigation.Brain,117, 1055–1071.

    Article  PubMed  Google Scholar 

  • Lockhart, R. S., &Craik, F. I. M. (1990). Levels of processing: A retrospective commentary on a framework for memory research.Canadian Journal of Psychology,44, 87–112.

    Google Scholar 

  • Lockhart, R. S., Craik, F. I. M., &Jacoby, L. L. (1976). Depth of processing, recognition and recall. In J. Brown (Ed.),Recall and recognition (pp. 75–102). New York: Wiley.

    Google Scholar 

  • Markowitsch, H. J. (1995). Anatomical basis of memory disorders. In M. S. Gazzaniga (Ed.),The cognitive neurosciences (pp. 765–779). Cambridge, MA: MIT Press.

    Google Scholar 

  • Markowitsch, H. J., &Pritzel, M. (1985). The neuropathology of amnesia.Progress in Neurobiology,25, 189–287.

    Article  PubMed  Google Scholar 

  • Markowitsch, H. J., &Tulving, E. (1994a). Cognitive processes and cerebral cortical fundi: Findings from positron-emission tomography studies.Proceedings of the National Academy of Science,91, 10507–10511.

    Article  Google Scholar 

  • Markowitsch, H. J., &Tulving, E. (1994b). Cognitive processing in cerebral cortical sulci.Neuroreport,6, 413–418.

    Article  Google Scholar 

  • McIntosh, A. R., &Gonzalez-Lima, F. (1994). Structural equation modeling and its application to network analysis in functional brain imaging.Human Brain Mapping,2, 2–22.

    Article  Google Scholar 

  • Mesulam, M.-M. (1990). Large-scale neurocognitive networks and distributed processing for attention, language, and memory.Annals of Neurology,28, 597–613.

    Article  PubMed  Google Scholar 

  • Molchan, S. E., Sunderland, T., McIntosh, A. R., Herscovitch, P., &Schreurs, B. G. (1994). A functional anatomical study of associative learning in humans.Proceedings of the National Academy of Science,91, 8122–8126.

    Article  Google Scholar 

  • Moscovitch, M., Kapur, S., Köhler, S., &Houle, S. (1995). Distinct neural correlates of visual long-term memory for spatial location and object identity: A positron emission tomography (PET) study in humans.Proceedings of the National Academy of Science,92, 3721–3725.

    Article  Google Scholar 

  • Nyberg, L.,McIntosh, A. R.,Cabeza, R.,Nilsson, L.-G.,Houle, S.,Habib, R., &Tulving, E. (in press). Network analysis of PET rCBF data: Ensemble inhibition during episodic memory retrieval.Journal of Neuroscience.

  • Nyberg, L., Tulving, E., Habib, R., Nilsson, L.-G., Kapur, S., Houle, S., Cabeza, R., &McIntosh, A. R. (1995). Functional brain maps of retrieval mode and recovery of episodic informationNeuroreport,7, 249–252.

    PubMed  Google Scholar 

  • Owen, A. M.,Milner, B.,Petrides, M., &Evans, A. C. (in press). A specific role for the right parahippocampal gyrus in the retrieval of object-location: A positron emission tomography study.Journal of Cognitive Neuroscience.

  • Pardo, J. V., &Fox, P. T. (1993). Preoperative assessment of the cerebral hemispheric dominance for language with CBF PET.Human Brain Mapping,1, 57–68.

    Article  Google Scholar 

  • Paulesu, E., Frith, C. D., &Frackowiak, R. S. J. (1993). The neural correlates of the verbal component of working memory.Nature,362, 342–345.

    Article  PubMed  Google Scholar 

  • Petersen, S. E., Corbetta, M., Miezin, F. M., &Shulman, G. L. (1994). PET studies of parietal involvement in spatial attention: Comparison of different task types.Canadian Journal of Experimental Psychology,48, 319–338.

    PubMed  Google Scholar 

  • Petersen, S. E., &Fiez, J. A. (1993). The processing of single words studied with positron emission tomography.Annual Review of Neuroscience,16, 509–530.

    Article  PubMed  Google Scholar 

  • Petersen, S. E., Fox, P. T., Posner, M. I., Mintun, M. [A.], &Raichle, M. E. (1988). Positron emission tomographic studies of the cortical anatomy of single-word processing.Nature,331, 585–589.

    Article  PubMed  Google Scholar 

  • Petersen, S. E., Fox, P. T., Snyder, A. Z., &Raichle, M. E. (1990, August 31). Activation of extrastriate and frontal cortical areas by visual words and word-like stimuli.Science,249, 1041–1044.

    Article  PubMed  Google Scholar 

  • Petrides, M., Alivasatos, B., &Evans, A. C. (1995). Functional activation of the human ventrolateral frontal cortex during mnemonic retrieval of verbal information.Proceedings of the National Academy of Science,92, 5803–5807.

    Article  Google Scholar 

  • Petrides, M., Alivasatos, B., Evans, A. C., &Meyer, E. (1993). Dissociation of human mid-dorsolateral from posterior dorsolateral frontal cortex in memory processing.Proceedings of the National Academy of Science,90, 873–877.

    Article  Google Scholar 

  • Petrides, M., Alivisatos, B., Meyer, E., &Evans, A. C. (1993). Functional activation of the human frontal cortex during the performance of verbal working memory tasks.Proceedings of the National Academy of Science,90, 878–882.

    Article  Google Scholar 

  • Posner, M. I., &Raichle, M. E. (1994).Images of mind. New York: Scientific American Books.

    Google Scholar 

  • Price, C., Wise, R., Ransay, S., Friston, K. [J.], Howard, D., Patterson, K., &Frackowiak, R. [S. J.] (1992). Regional response differences within the human auditory cortex when listening to words.Neuroscience Letters,146, 179–182.

    Article  PubMed  Google Scholar 

  • Raichle, M. E. (1994a). Images of the mind: Studies with modern imaging techniques.Annual Review of Psychology,45, 333–356.

    Article  PubMed  Google Scholar 

  • Raichle, M. E. (1994b, April). Visualizing the mind.Scientific American, pp. 58–64.

  • Raichle, M. E., Fiez, J. A., Videen, T. O., MacLeod, A.-M. K., Pardo, J. V., Fox, P. T., &Petersen, S. E. (1994). Practice-related changes in human brain functional anatomy during nonmotor learning.Cerebral Cortex,4, 8–26.

    Article  PubMed  Google Scholar 

  • Roland, P. E. (1982). Cortical regulation of selective attention in man: A regional cerebral blood flow study.Journal of Neurophysiology,48, 1059–1078.

    PubMed  Google Scholar 

  • Roland, P. E., Kawashima, R., Gulyas, B., &O’Sullivan, B. (1995). Positron emission tomography in cognitive neuroscience: Methodological constraints, strategies, and examples from learning and memory. In M. S. Gazzaniga (Ed.),The cognitive neurosciences (pp. 781–788). Cambridge, MA: MIT Press.

    Google Scholar 

  • Schacter, D. L. (1987). Memory, amnesia, and frontal lobe dysfunction.Psychobiology,15, 21–36.

    Google Scholar 

  • Schacter, D. L., Alpert, N. M., Savage, C. R., Rauch, S. L., &Albert, M. S. (1996). Conscious recollection and the human hippocampal formation: Evidence from positron emission tomography.Proceedings of the National Academy of Science,93, 321–325.

    Article  Google Scholar 

  • Schacter, D. L., Reiman, E., Uecker, A., Polster, M. R., Yung, L. S., &Cooper, L. A. (1995). Brain regions associated with retrieval of structurally coherent visual information.Nature,368, 633–635.

    Google Scholar 

  • Schacter, D. L.,Savage, C. R.,Alpert, N. M.,Rauch, S. L., &Albert, M. (in press). The role of the hippocampus and frontal cortex in age-related memory loss.Neuroreport.

  • Seitz, R., &Roland, P. (1992). Learning of sequential finger movements in man: A combined kinematic and positron emission tomography (PET) study.European Journal of Neuroscience,4, 154–165.

    Article  PubMed  Google Scholar 

  • Sergent, J., Ohta, S., &MacDonald, B. (1992). Functional neuroanatomy of face and object processing.Brain,115, 15–36.

    Article  PubMed  Google Scholar 

  • Shallice, T., Fletcher, P., Frith, C. D., Grasby, P., Frackowiak, R. S. J., &Dolan, R. J. (1994). Brain regions associated with acquisition and retrieval of verbal episodic memory.Nature,368, 633–635.

    Article  PubMed  Google Scholar 

  • Snodgrass, J. G., &Vanderwart, M. A. (1980). A standardized set of 260 pictures: Norms for name agreement, image agreement, familiarity, and visual complexity.Journal of Experimental Psychology: Human Learning & Memory,6, 174–215.

    Article  Google Scholar 

  • Squire, L. R., Ojemann, J. G., Miezin, F. M., Petersen, S. E., Videen, T. O., &Raichle, M. E. (1992). Activation of the hippocampus in normal humans: A functional anatomical study of memory.Proceedings of the National Academy of Science,89, 1837–1841.

    Article  Google Scholar 

  • Squire, L. R., &Zola-Morgan, S. (1991, September 20). The medial temporal lobe memory system.Science,253, 1380–1386.

    Article  PubMed  Google Scholar 

  • Steinmetz, H., &Seitz, R. J. (1991). Functional anatomy of language processing: Neuroimaging and the problem of individual variability.Neuropsychologia,29, 1149–1161.

    Article  PubMed  Google Scholar 

  • Stuss, D. T., &Benson, D. F. (1986).The frontal lobes. New York: Raven Press.

    Google Scholar 

  • Talairach, J., &Tournoux, P. (1988).Co-planar steorotaxic atlas of the human brain. New York: Thieme Medical Publishers.

    Google Scholar 

  • Tamas, L. B., Shibasaki, T., Horikoshi, S., &Ohye, C. (1993). General activation of cerebral metabolism with speech: A PET study.International Journal of Psychophysiology,14, 199–208.

    Article  PubMed  Google Scholar 

  • Tulving, E. (1972). Episodic and semantic memory. In E. Tulving & W. Donaldson (Eds.),Organization of memory (pp. 381–403). New York: Academic Press.

    Google Scholar 

  • Tulving, E. (1983).Elements of episodic memory. New York: Oxford University Press.

    Google Scholar 

  • Tulving, E. (1993). What is episodic memory?Current Perspectives in Psychological Science,2, 67–70.

    Article  Google Scholar 

  • Tulving, E., Kapur, S., Craik, F. I. M., Moscovitch, M., &Houle, S. (1994). Hemispheric encoding/retrieval asymmetry in episodic memory: Positron emission tomography findings.Proceedings of the National Academy of Science,91, 2016–2020.

    Article  Google Scholar 

  • Tulving, E., Kapur, S., Markowitsch, H. J., Craik, F. I. M., Habib, R., &Houle, S. (1994). Neuroanatomical correlates of retrieval in episodic memory: Auditory sentence recognition.Proceedings of the National Academy of Science,91, 2012–2015.

    Article  Google Scholar 

  • Tulving, E., &Kroll, N. (1995). Novelty assessment in the brain and long-term memory encoding.Psychonomic Bulletin & Review,2, 387–390.

    Article  Google Scholar 

  • Tulving, E., Markowitsch, H. J., Craik, F. I. M., Habib, R., &Houle, S. (1996). Novelty and familiarity activations in PET studies of memory encoding and retrieval.Cerebral Cortex,6, 71–79.

    Article  PubMed  Google Scholar 

  • Tulving, E., Markowitsch, H. J., Kapur, S., Habib, R., &Houle, S. (1994). Novelty encoding networks in the human brain: Positron emission tomography data.Neuroreport,5, 2525–2528.

    Article  PubMed  Google Scholar 

  • Tulving, E., &Pearlstone, Z. (1966). Availability versus accessibility of information in memory for words.Journal of Verbal Learning & Verbal Behavior,5, 381–391.

    Article  Google Scholar 

  • Wheeler, M. A., Stuss, D. T., &Tulving, E. (1995). Frontal lobe damage produces episodic memory impairment.Journal of the International Neuropsychological Society,1, 525–536.

    Article  PubMed  Google Scholar 

  • Wilson, F. A., &Rolls, E. T. (1993). The effects of stimulus novelty and familiarity on neuronal activity in the amygdala of monkeys performing recognition memory tasks.Experimental Brain Research,93, 367–382.

    Article  Google Scholar 

  • Wise, R., Chollet, F., Hadar, U., Friston, K. [J.], Hoffner, E., &Frackowiak, R. [S. J.] (1991). Distribution of cortical neural networks involved in word comprehension and word retrieval.Brain,114, 1803–1817.

    Article  PubMed  Google Scholar 

  • Worsley, K. J., Evans, A. C., Marrett, S., &Neelin, P. (1992). A threedimensional statistical analysis for CBF activation studies in human brain.Journal of Cerebral Blood Flow & Metabolism,12, 900–918.

    Google Scholar 

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  1. Rotman Research Institute of Baycrest Centre, University of Toronto, North York, Ontario, Canada

    Lars Nyberg, Roberto Cabeza & Endel Tulving

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  1. Lars Nyberg
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  2. Roberto Cabeza
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  3. Endel Tulving
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Correspondence to Lars Nyberg.

Additional information

We thank John Gabrieli, Roger Ratcliff, Dan Schacter, and one anonymous reviewer for valuable comments. We also thank Randy Buckner, Paul Fletcher, Narinder Kapur, and Stefan Köhler for assistance.

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Nyberg, L., Cabeza, R. & Tulving, E. PET studies of encoding and retrieval: The HERA model. Psychonomic Bulletin & Review 3, 135–148 (1996). https://doi.org/10.3758/BF03212412

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Keywords

  • Positron Emission Tomography
  • Episodic Memory
  • Positron Emission Tomography Study
  • Target Task
  • Transient Global Amnesia