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Lipid profile and nutritional intake in children and adolescents with Type 1 diabetes improve after a structured dietician training to a Mediterranean-style diet

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Abstract

Aim: To evaluate if nutritional intakes and lipid profile fulfill international guidelines and recommendations before and after a structured dietician training to a Mediterranean-style diet in an Italian pediatric population with Type 1 diabetes. Methods: A 6-month prospective cohort study. Baseline and after-intervention nutritional intakes, lipid profile, glycated hemoglobin (HbA1c), and clinical parameters of 96 children and adolescents with Type 1 diabetes were assessed. A comparative computerized system which was approved and validated by the Italian Diabetologist Association was used to define the amounts of nutrients. Results: At baseline mean daily dietary intakes of carbohydrates, proteins, and lipids were respectively (mean ±SEM) 51.8 ±0.5, 15.9 ±0.2, 33.8 ±0.6%, with a contribution of cholesterol of 248.7 ±12.5 mg/day. Fiber assumption was 18.0 ±0.4 g/day. The 64.5% and 29.1% (p<0.0001) of subjects had at least one lipid parameter higher than 75th and 95th percentiles, respectively, of selected cut points (American Diabetes Associationguidelines for total and LDL-cholesterol and American Academy of Pediatrics standards for HDL-cholesterol and triglycerides). Six months after the dietician intervention, dietary lipids and cholesterol decreased (p<0.0001) while fibers (p<0.0001) increased. LDL-cholesterol, non-HDL-cholesterol, and total cholesterol: HDL-cholesterol ratios significantly decreased (p<0.001) with a reduction of rate of subjects with at least one pathological lipid parameter (p<0.01) independently by weight and glucose control. Conclusions: Italian pediatric subjects with Type 1 diabetes present a balanced diet with exception of lipids intake and a suboptimal lipid profile. A structured dietician training to a Mediterranean-style diet improves the quality of nutrient intakes being followed by a reduction of LDL-cholesterol, non-HDL-cholesterol, and total cholesterol: HDL-cholesterol ratios.

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Authors and Affiliations

  1. Division of Pediatrics, Department of Health Sciences, University of Piemonte Orientale, Novara, Italy

    F. Cadario, F. Prodam, S. Pasqualicchio, S. Bellone, I. Bonsignori, I. Demarchi, A. Monzani & G. Bona MD (Prof)

  2. Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), University of Piemonte Orientale, Novara, Italy

    F. Cadario & G. Bona MD (Prof)

  3. Division of Endocrinology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy

    F. Prodam

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  1. F. Cadario
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Cadario, F., Prodam, F., Pasqualicchio, S. et al. Lipid profile and nutritional intake in children and adolescents with Type 1 diabetes improve after a structured dietician training to a Mediterranean-style diet. J Endocrinol Invest 35, 160–168 (2012). https://doi.org/10.3275/7755

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