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Assessing the Impact of Antistress Pharmacologic Agents on Serological Status to Prevent Tenosynovitis in Chickens

  • ANIMAL SCIENCE AND VETERINARY MEDICINE
  • Published:
Russian Agricultural Sciences Aims and scope

Abstract

The survey to measure the impact of antistress pharmacologic agents, particularly the SPAO-complex product along with the SPAO-KD feed additive, on the immune status of chickens to prevent tenosynovitis was carried out. In order to conduct the surveys, the chickens were allocated into three groups of 32 000 heads each to build the parent flock. Chickens in the first group served as the control. The specimens in the second test group were provided with the SPAO-KD feed additive in the mixed fodder. The poultry in the third test group were provided with the SPAO-complex pharmocological-composition product with water. The dietary preventive agents were used at a dose of 185 mg/kg body weight for 5 days in the reference live vaccine used for vaccination: 3 days before vaccinations, on the day of vaccination, and 1 day after vaccination. Poultry immunization against reovirus tenosynovitis was carried out according to the technology for population vaccination. A dried live vaccine against avian reovirus tenosynovitis was used to vaccinate the chickens at the age of 1 and 4 weeks. It was produced from an attenuated strain 1133 of avian reovirus isolated from tenosynovitis. The seroconversion rates in quantitative and qualitative manners in the reference test agents were assessed 7 and 14 days after the first vaccination and 14 and 21 days after the second vaccination. The dietary SPAO-KD feed additive and the water-soluble SPAO-complex pharmacological product contributed to an increase in the levels of postvaccination antibodies 1.6- and 2.6-fold, respectively, and the vaccination indices 1.6- and 3.5-fold, respectively. The SPAO complex product contributed to reducing the coefficient of variation of postvaccination antibodies by 25.7%. Taking antistress therapies under the effects of immunologic load factors provided the poultry welfare benefit and improved the production of day-old chicks and the poultry live weight gain by 0.79–3.5, 0.55–4.22, and 0.88–6.44%, respectively.

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Authors and Affiliations

  1. South Ural State Agricultural University, 457100, Troitsk, Chelyabinsk oblast, Russia

    A. V. Miftakhutdinov, N. A. Zhuravel & V. V Ponomarenko

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  1. A. V. Miftakhutdinov
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  2. N. A. Zhuravel
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  3. V. V Ponomarenko
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Correspondence to N. A. Zhuravel.

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Conflict of interest. The authors declare that they have no conflict of interests.

Statement on the welfare of animals. All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.

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Translated by O. Zhiryakova

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Miftakhutdinov, A.V., Zhuravel, N.A. & Ponomarenko, V.V. Assessing the Impact of Antistress Pharmacologic Agents on Serological Status to Prevent Tenosynovitis in Chickens. Russ. Agricult. Sci. 47, 518–523 (2021). https://doi.org/10.3103/S1068367421050128

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