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Generalized model of polypeptide chain with limitations on the length of helical fractions

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Journal of Contemporary Physics (Armenian Academy of Sciences) Aims and scope

Abstract

A model is proposed described by a Hamiltonian consisting of two terms corresponding to Hamiltonians of the generalized model of polypeptide chain (GMPC) with different scales of interaction. We consider a case where the long-scale interaction corresponds to attraction, while the short-scale interaction corresponds to repulsion; this case models the melting of the system in compact packing conditions (globularized polypeptide or DNA in capsid). In the framework of the transfer-matrix approach we calculate the correlation length and the helicity degree. It is shown that the temperature dependence of the correlation length is determined by the complex second eigenvalue of the transfer-matrix. In this regime the system displays a new type of correlations when the melting interval cannot be a measure of the system cooperativity.

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Original Russian Text © Sh.A. Tonoyan, G.N. Hayrapetyan, A.V. Tsarukyan, Y.Sh. Mamasakhlisov, V.F. Morozov, 2008, published in Izvestiya NAN Armenii, Fizika, 2008, Vol. 43, No. 4, pp. 311–318.

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Tonoyan, S.A., Hayrapetyan, G.N., Tsarukyan, A.V. et al. Generalized model of polypeptide chain with limitations on the length of helical fractions. J. Contemp. Phys. 43, 203–207 (2008). https://doi.org/10.3103/S1068337208040099

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  • DOI: https://doi.org/10.3103/S1068337208040099

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