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YVO4:Yb,Er Upconversion Nanoparticles for Biovisualization: A Biocompatible Probe in Grape Snails

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Bulletin of the Russian Academy of Sciences: Physics Aims and scope

Abstract

YVO4:Yb,Er upconversion nanoparticles (UCNPs) are synthesized to study the possibility of using them as nanoprobes to solve biological problems. Aqueous colloidal solutions of UCNPs are injected into the bodies of grape snails. When preparations from animal organs are irradiated with a continuous wave (CW) laser at a wavelength of 980 nm, luminescence is observed in the region of 520–560 nm, due to radiative transitions in Er3+ ions. A comparative analysis of the behavioral activity of animals with injected nanoparticles and control animals with no nanoparticles reveals no signs of toxicity. The nanoparticles are promising as luminescence nanoprobes in biological problems.

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Funding

The synthesis of UCNPs was supported by the Government of the Russian Federation under Decree No. 220, Contract No. 14.W03.31.0028 with the Zavoisky Physicotechnical Institute, Kazan Scientific Center, Russian Academy of Sciences as the leading organization. The spectroscopic studies were supported by the Russian Foundation for Basic Research, project nos. 19-02-00569 and 20-02-00545. The experiments with animals were performed as part of a State Task.

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Authors and Affiliations

  1. Zavoisky Physical-Technical Institute, Federal Research Center “Kazan Scientific Center,” Russian Academy of Sciences, 420029, Kazan, Tatarstan, Russia

    A. G. Shmelev, V. G. Nikiforov, D. K. Zharkov, V. V. Andrianov, L. N. Muranova, A. V. Leontyev, Kh. L. Gainutdinov, V. S. Lobkov & P. R. Hemmer

  2. Kazan Federal University, 420008, Kazan, Tatarstan, Russia

    V. V. Andrianov, L. N. Muranova & Kh. L. Gainutdinov

  3. National Center for Laser and Optoelectronics, King Abdulaziz City for Science and Technology, 11442, Riyadh, Saudi Arabia

    M. H. Alkahtani

  4. Institute for Quantum Science and Engineering Texas A&M University, College Station, 77843, TX, USA

    P. R. Hemmer

Authors
  1. A. G. Shmelev
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  2. V. G. Nikiforov
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  3. D. K. Zharkov
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  4. V. V. Andrianov
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  5. L. N. Muranova
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  6. A. V. Leontyev
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  7. Kh. L. Gainutdinov
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  8. V. S. Lobkov
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  9. M. H. Alkahtani
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  10. P. R. Hemmer
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Corresponding author

Correspondence to A. G. Shmelev.

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The authors declare there was no conflict of interest. All applicable international, national, and/or institutional guidelines for the care and use of animals were followed.

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Translated by O. Zhukova

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Shmelev, A.G., Nikiforov, V.G., Zharkov, D.K. et al. YVO4:Yb,Er Upconversion Nanoparticles for Biovisualization: A Biocompatible Probe in Grape Snails. Bull. Russ. Acad. Sci. Phys. 84, 1439–1443 (2020). https://doi.org/10.3103/S1062873820120357

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  • DOI: https://doi.org/10.3103/S1062873820120357

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