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Developing a standard phantom of the human eye for internal dose assessment

  • Proceedings of the LXIV International Conference “Nuclei 2014: Fundamental Problems and Applications of Nuclear Physics, from Nanotechnology to Space” (LXIV International Meeting on Nuclear Spectroscopy and the Structure of Atomic Nuclei)
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Bulletin of the Russian Academy of Sciences: Physics Aims and scope

Abstract

This work is a continuation of the development of Astatine-211, a new α-emitter radiopharmaceutical for treating cancer of the thyroid gland. The internal doses in a patient’s organs, e.g., the eye and the lens of the eye, are estimated using the GEANT-4 software for calculating absorbed doses in different organs with allowance for the complex anatomy of the human body. The results of calculations show that with the same therapeutic dose in an irradiated organ (the thyroid gland), the use of Astatine-211 radiopharmaceutical reduces the radiation dose of the eye by several orders of magnitude, compared to the use of pharmaceuticals containing 131I.

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References

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Authors and Affiliations

  1. Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, Moscow, 119991, Russia

    O. V. Fotina, V. A. Drozdov, D. O. Eremenko, S. Yu. Platonov & O. A. Yuminov

  2. Faculty of Physics, Moscow State University, Moscow, 119991, Russia

    O. V. Fotina, T. V. Gulyaeva, D. O. Eremenko & S. Yu. Platonov

Authors
  1. O. V. Fotina
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  2. T. V. Gulyaeva
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  3. V. A. Drozdov
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  4. D. O. Eremenko
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  5. S. Yu. Platonov
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  6. O. A. Yuminov
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Corresponding author

Correspondence to O. V. Fotina.

Additional information

Original Russian Text © O.V. Fotina, T.V. Gulyaeva, V.A. Drozdov, D.O. Eremenko, S.Yu. Platonov, O.A. Yuminov, 2015, published in Izvestiya Rossiiskoi Akademii Nauk. Seriya Fizicheskaya, 2015, Vol. 79, No. 4, pp. 500–502.

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Fotina, O.V., Gulyaeva, T.V., Drozdov, V.A. et al. Developing a standard phantom of the human eye for internal dose assessment. Bull. Russ. Acad. Sci. Phys. 79, 458–460 (2015). https://doi.org/10.3103/S1062873815040097

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  • DOI: https://doi.org/10.3103/S1062873815040097

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