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Using Mössbauer spectroscopy to interpret histological analysis data of iron-containing compounds in rat brain

  • Proceedings of the 12th International Conference “Mössbauer Spectroscopy and its Applications”
  • Published:
Bulletin of the Russian Academy of Sciences: Physics Aims and scope

Abstract

Ferrofluid containing magnetic nanoparticles of Fe3O4 was introduced into the rat brain ventricle via direct transcranial injection. Three months following the injection, the rats were euthanized and their brains investigated by means of histology and Mössbauer spectroscopy. It is demonstrated that the nanoparticles completely decomposed and were cleared from the brain, while the concomitant chemical compound accompanying the ferrofluid synthesis remained intact in the brain.

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Authors and Affiliations

  1. National Research Center Kurchatov Institute, Moscow, 123182, Russia

    D. M. Polikarpov, R. R. Gabbasov, V. M. Cherepanov & V. Ya. Panchenko

  2. Institute of Physics and Technology, Russian Academy of Sciences, Moscow, 117218, Russia

    M. A. Chuev

Authors
  1. D. M. Polikarpov
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  2. R. R. Gabbasov
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  3. V. M. Cherepanov
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  4. M. A. Chuev
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  5. V. Ya. Panchenko
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Corresponding author

Correspondence to D. M. Polikarpov.

Additional information

Original Russian Text © D.M. Polikarpov, R.R. Gabbasov, V.M. Cherepanov, M.A. Chuev, V.Ya. Panchenko, 2013, published in Izvestiya Rossiiskoi Akademii Nauk. Seriya Fizicheskaya, 2013, Vol. 77, No. 6, pp. 803–806.

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Polikarpov, D.M., Gabbasov, R.R., Cherepanov, V.M. et al. Using Mössbauer spectroscopy to interpret histological analysis data of iron-containing compounds in rat brain. Bull. Russ. Acad. Sci. Phys. 77, 730–733 (2013). https://doi.org/10.3103/S1062873813060257

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  • DOI: https://doi.org/10.3103/S1062873813060257

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